Skip Navigation
Skip to contents

PHRP : Osong Public Health and Research Perspectives

OPEN ACCESS
SEARCH
Search

Author index

Page Path
HOME > Articles and issues > Author index
Search
Atif Kamal 1 Article
Hematological Evidence of Occupational Exposure to Chemicals and Other Factors among Auto-Repair Workers in Rawalpindi, Pakistan
Atif Kamal, Riffat Naseem Malik
Osong Public Health Res Perspect. 2012;3(4):229-238.   Published online December 31, 2012
DOI: https://doi.org/10.1016/j.phrp.2012.10.003
  • 1,801 View
  • 20 Download
  • 15 Citations
AbstractAbstract PDF
Objectives
Occupational exposure to aromatic solvents causes many serious health hazards to workers, especially if an ambient environment increases the exposure during routine working hours. This study was conducted on two related groups, i.e., automobile mechanics (MCs) and automobile spray painters (PNs), with an effort to analyze effects of chemical exposure on hematological parameters, keeping a focus on environmental parameters and workers’ personal behavioral characteristics that could be held responsible for increasing exposure risk.
Methods
A preliminary survey of various chemicals used in these places was done, and 78 blood samples were collected from three groups (control, n = 24; mechanics, n = 25; painters, n = 29). Demographic features of workers were recorded through a short questionnaire.
Results

Results
showed that mean red blood cell (RBC) count was lower both in MCs [t(51) = 2.38, p < 0.021, r = 0.32] and in PNs [t(47) = 2.12, p < 0.03, r = 0.29], whereas mean hemoglobin (Hb) was significantly lower in MCs [t(51) = 2.5, p = 0.017, r = 0.33]. Combined data for exposed groups for smokers (SMs) versus nonsmokers (NSs) showed that SMs had a significantly lower number (RBC count: t(52) = 2.28, p < 0.027, r = 0.25; Hb count: t(52) = 2.71, p < 0.009, r = 0.30] of these parameters than NSs, even compared to the control group. Moreover, logistic regression results showed that smoking is a significant predictor of reduction in RBC and Hb counts, besides occupational exposure and work experience to a little extent among exposed workers. Mean white blood cell count [t(47) = 2.63, p < 0.01, r=0.35], mean corpuscle volume [t(47)= –2.82, p = 0.007, r = 0.29], and packed cell volume [t(47)= –2.28, p = 0.027, r = 31] were higher exclusively in painters, which could be related to exposure to benzene in addition to isocyanate.
Conclusion
It appeared that workplace exposure may be complex due to interaction of multiple factors and PNs face much more exposure to isocyanate and aromatic solvents than MCs, which had significant effects on their hematopoiesis. Smoking enhances exposure risk manifolds, and among MCs it showed combined effects along with occupational exposure. There is a need to create awareness among these workers to adopt self-safety measures during routine tasks and also of a separate study to elucidate actual occupational exposure among them, eliminating confounding factors.

Citations

Citations to this article as recorded by  
  • The toxic effects of spent crankcase oil exposures; systematic review and meta-analysis
    Grace Eserophe Bekibele, Francis Chukwuma Anacletus, Kingsley Chukwuemeka Patrick-Iwuanyanwu
    Toxicological Research.2022; 38(2): 113.     CrossRef
  • Study of general health and haematological status of automobile garage workers exposed to toxicants: Comparison with office workers
    SudhirPrabhu Haladi, Faizan Kalekhan, Paul Simon, ManjeshwarShrinath Baliga
    Hamdan Medical Journal.2022; 15(1): 29.     CrossRef
  • A Preliminary Assessment of Health and Safety in the Automobile Industry in Brunei Darussalam: Workers’ Knowledge and Practice of Organic Solvents
    Hazimah Hasylin, Khadizah H. Abdul-Mumin, Pg-Khalifah Pg-Hj-Ismail, Ashish Trivedi, Kyaw Naing Win
    International Journal of Environmental Research an.2022; 19(23): 15469.     CrossRef
  • Species and characteristics of volatile organic compounds emitted from an auto-repair painting workshop
    M. Y. Song, H. Chun
    Scientific Reports.2021;[Epub]     CrossRef
  • Urinary toluene levels and adverse health symptoms among automotive garage workers, Nakhon Si Thammarat province, Thailand
    Somsiri Decharat
    Environmental Analysis Health and Toxicology.2021; 36(3): e2021018.     CrossRef
  • EXAMINATION OF APOPTOTIC CHANGES IN AROMATIC HYDROCARBON BENZENE ADMINISTERED RAT TESTICULAR TISSUE WITH HISTOPATHOLOGICAL METHODS
    Eda YİLDİZHAN, Leyla CANPOLAT KOYUTÜRK, Murat AKKUŞ, Nalan KAYA TEKTEMUR, Ebru GÖKALP ÖZKORKMAZ, Fırat AŞIR
    Middle East Journal of Science.2021; 7(1): 1.     CrossRef
  • Assessment of hematological parameters of petrol filling workers at petrol stations in Gondar town, Northwest Ethiopia: a comparative cross-sectional study
    Sisay Getu, Elias Shiferaw, Mulugeta Melku
    Environmental Health and Preventive Medicine.2020;[Epub]     CrossRef
  • Elevated exposure to polycyclic aromatic hydrocarbons (PAHs) may trigger cancers in Pakistan: an environmental, occupational, and genetic perspective
    Muhammad Yasir Abdur Rehman, Malik Mumtaz Taqi, Imran Hussain, Jawad Nasir, Syed Hussain Haider Rizvi, Jabir Hussain Syed
    Environmental Science and Pollution Research.2020; 27(34): 42405.     CrossRef
  • Reduced Haematopoietic Output in Automobile Mechanics and Sprayers with Chronic Exposure to Petrochemicals: A Case-Control Study in Cape Coast, Ghana
    Patrick Adu, Richard Pobee, Aaron Awuah, Paul B. Asiamah, Festus Amoani, Sampson Gyabaa
    Journal of Environmental and Public Health.2018; 2018: 1.     CrossRef
  • Assessment of Hematotoxicity and Genotoxicity among paint Workers in Assiut Governorate: a case control study
    Nahed Abdel Maksoud, Khaled Abdel Aal, Nagwa Ghandour, Mona El-Baz, Eman Shaltout
    Egyptian Journal of Forensic Sciences.2018;[Epub]     CrossRef
  • Pulmonary Toxicity Induced by N-Hexane in Wistar Male Rats After Oral Subchronic Exposure
    Imane Bouakkaz, Kamel Khelili, Tarek Rebai, Andreas Lock
    Dose-Response.2018; 16(4): 155932581879956.     CrossRef
  • Occupational Respiratory Diseases of Miners from Two Gold Mines in Ghana
    Esther Ayaaba, Yan Li, Jiali Yuan, Chunhui Ni
    International Journal of Environmental Research an.2017; 14(3): 337.     CrossRef
  • Hepatotoxicity and genotoxicity of gasoline fumes in albino rats
    Folarin O. Owagboriaye, Gabriel A. Dedeke, Joseph S. Ashidi, A.A. Aladesida, Wasiu E. Olooto
    Beni-Suef University Journal of Basic and Applied .2017; 6(3): 253.     CrossRef
  • Health and carcinogenic risk evaluation for cohorts exposed to PAHs in petrochemical workplaces in Rawalpindi city (Pakistan)
    Atif Kamal, Alessandra Cincinelli, Tania Martellini, Ilaria Palchetti, Francesca Bettazzi, Riffat Naseem Malik
    International Journal of Environmental Health Rese.2016; 26(1): 37.     CrossRef
  • Benzene exposure among auto-repair workers from workplace ambience: A pioneer study from Pakistan
    Atif Kamal, Audil Rashid
    International Journal of Occupational Medicine and.2014; 27(5): 830.     CrossRef

PHRP : Osong Public Health and Research Perspectives