- Exposure of Infants to Aflatoxin M1 from Mother's Breast Milk in Ilam, Western Iran
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Farajollah Maleki, Soghra Abdi, Elaham Davodian, Karimeh Haghani, Salar Bakhtiyari
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Osong Public Health Res Perspect. 2015;6(5):283-287. Published online October 31, 2015
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DOI: https://doi.org/10.1016/j.phrp.2015.10.001
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Abstract
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- Objectives
Aflatoxins as a highly toxic group of mycotoxins are present in the environment and foodstuff. These have been reported to cause serious health problems in humans. Since aflatoxin M1 (AFM1) is excreted into breast milk, investigating the exposure of infants to AFM1 is of special concern. Methods
In the present study, breast milk samples were collected from 85 lactating mothers in Ilam province, Iran, and the levels of AFM1 were analyzed using the enzyme-linked immunosorbent assay-based technique. AFM1 was detected in breast milk of all lactating women. The mean contamination level was 5.91 ± 2.031 ng/L, ranging from 2 ng/L to 10 ng/L. Results
Multiple regression analysis indicated no significant associations of consumption of milk and dairy products, meat, fish, legumes, grain products, fruits, and nuts with the concentration of AFM1 in breast milk. Furthermore, no significant association was observed between AFM1 concentration and anthropometric data of infants. Conclusion
In western parts of Iran, lactating mothers and their infants could be at risk of aflatoxin B1 and AFM1 exposure, respectively. Therefore, in Iran, the evaluation of AFM1 in human breast milk as a biomarker for postnatal exposure of infants to this carcinogen requires more attention in different regions and various seasons.
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Citations
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- Determination of aflatoxin M1 and ochratoxin A in breast milk in rural centers of Yazd, Iran: Exposure assessment and risk characterization
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Yasemin Açar, Gamze Akbulut Current Nutrition Reports.2024; 13(1): 59. CrossRef - Risk of exposure to aflatoxin M1 through consumption of cow’s milk among children in Magadu, Morogoro
Anna Peter Mamiro, Haikael D. Martin, Neema Kassim Mycotoxin Research.2024; 40(2): 245. CrossRef - Aflatoxins: Source, Detection, Clinical Features and Prevention
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Ahmed Aljazzar, Waleed Rizk El-Ghareeb, Wageh Sobhy Darwish, Sherief M. Abdel-Raheem, Abdelazim M. Ibrahim, Eman E. Hegazy, Esraa A. Mohamed Environmental Science and Pollution Research.2022; 30(5): 13132. CrossRef - A promising innovative technique for mycotoxin detoxification from beverages using biofilms of lactic acid bacteria
Sahar Nahle, André El Khoury, Jean Claude Assaf, Nicolas Louka, Ali Chokr, Ali Atoui Innovative Food Science & Emerging Technologies.2022; 82: 103165. CrossRef - Human Breast Milk Contamination with Aflatoxins, Impact on Children’s Health, and Possible Control Means: A Review
Noreddine Benkerroum, Amir Ismail International Journal of Environmental Research an.2022; 19(24): 16792. CrossRef - miR-155 influences cell-mediated immunity in Balb/c mice treated with aflatoxin M1
Kobra Shirani, Bamdad Riahi Zanjani, Soghra Mehri, Kamal Razavi-Azarkhiavi, Ali Badiee, A. Wallace Hayes, John P. Giesy, Gholamreza Karimi Drug and Chemical Toxicology.2021; 44(1): 39. CrossRef - Human milk mycotoxin contamination: smoking exposure and breastfeeding problems
Esra Yasemin Memiş, Sıddıka Songül Yalçın The Journal of Maternal-Fetal & Neonatal Medicine.2021; 34(1): 31. CrossRef - Biological Control and Mitigation of Aflatoxin Contamination in Commodities
Ferenc Peles, Péter Sipos, Szilvia Kovács, Zoltán Győri, István Pócsi, Tünde Pusztahelyi Toxins.2021; 13(2): 104. CrossRef - Mycotoxin carry-over in breast milk and weight of infant in exclusively-breastfed infants
Esra Yasemin Memiş, Sıddıka Songül Yalçın, Suzan Yalçın Archives of Environmental & Occupational Health.2021; 76(6): 313. CrossRef - Physical and Chemical Methods for Reduction in Aflatoxin Content of Feed and Food
Péter Sipos, Ferenc Peles, Dóra Lili Brassó, Béla Béri, Tünde Pusztahelyi, István Pócsi, Zoltán Győri Toxins.2021; 13(3): 204. CrossRef - Biocontrol of Aflatoxins Using Non-Aflatoxigenic Aspergillus flavus: A Literature Review
Rahim Khan, Farinazleen Mohamad Ghazali, Nor Ainy Mahyudin, Nik Iskandar Putra Samsudin Journal of Fungi.2021; 7(5): 381. CrossRef - Aflatoxin Biosynthesis, Genetic Regulation, Toxicity, and Control Strategies: A Review
Rahim Khan, Farinazleen Mohamad Ghazali, Nor Ainy Mahyudin, Nik Iskandar Putra Samsudin Journal of Fungi.2021; 7(8): 606. CrossRef - Aflatoxin M1 contamination level in Iranian milk and dairy products: a systematic review and meta-analysis
S. Hamzeh Pour, S. Mahmoudi, S. Masoumi, S. Rezaie, A. Barac, M. Ranjbaran, S. Oliya, F. Mehravar, E. Sasani, F. Noorbakhsh, S. Khodavaisy World Mycotoxin Journal.2020; 13(1): 67. CrossRef - Levels of Aflatoxin M1 and selected heavy metals (Pb, Cd, Cr, Cu, Zn, Fe, As, and Hg) in the breast milk of lactating mothers in South Eastern, Nigeria
Chidinma Lynda Ekeanyanwu, Chinwe Sylvanus Alisi, Raphael Chukwuma Ekeanyanwu Food Control.2020; 112: 107150. CrossRef - Dietary mycotoxins exposure and child growth, immune system, morbidity, and mortality: a systematic literature review
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Gonca Karayağiz Muslu, Mehmet Özdemir Biological Research For Nursing.2020; 22(3): 362. CrossRef - Aflatoxin exposure among lactating women in southern Ethiopia
Bergene Boshe, Samson Gebremedhin, Fikadu Alemayehu, Mesfin Eshete, Mestawet Taye, Barbara J. Stoecker Food Science & Nutrition.2020; 8(12): 6738. CrossRef - An assessment of the occurrence and nutritional factors associated with aflatoxin M1, ochratoxin A, and zearalenone in the breast milk of nursing mothers in Hamadan, Iran
Fateme Samiee, Ava Kharazi, Jomana Elaridi, Masoumeh Taravati Javad, Mostafa Leili Toxicon.2020; 187: 209. CrossRef - Aflatoxin, fumonisin, ochratoxin, zearalenone and deoxynivalenol biomarkers in human biological fluids: A systematic literature review, 2001–2018
Belqes Ahmad Al-Jaal, Morana Jaganjac, Andrei Barcaru, Peter Horvatovich, Aishah Latiff Food and Chemical Toxicology.2019; 129: 211. CrossRef - Concentration and Prevalence of Aflatoxin M1 in Human Breast Milk in Iran: Systematic Review, Meta-Analysis, and Carcinogenic Risk Assessment: A Review
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Sarah Khan, Amir Ismail, Yun Yun Gong, Saeed Akhtar, Majid Hussain Food Control.2018; 91: 344. CrossRef - Immunotoxicity of aflatoxin M1: as a potent suppressor of innate and acquired immune systems in a subacute study
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Nor Shifa Shuib, Ahmad Makahleh, Salizawati Muhamad Salhimi, Bahruddin Saad Food Control.2017; 73: 966. CrossRef - Aflatoxin M1in human breast milk in Shahrekord, Iran and association with dietary factors
Tina Jafari, Aziz A. Fallah, Soleiman Kheiri, Abdolmajid Fadaei, Sayed Asadollah Amini Food Additives & Contaminants: Part B.2017; 10(2): 128. CrossRef - Biomonitoring of Mycotoxins in Human Breast Milk: Current State and Future Perspectives
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