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Volume 8(6); December 2017
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Editorial
Adolescents in Multi-Ethnic Families under Korean Ethnic Nationalism
Hae-Wol Cho, Chaeshin Chu
Osong Public Health Res Perspect. 2017;8(6):367-368.   Published online December 31, 2017
DOI: https://doi.org/10.24171/j.phrp.2017.8.6.01
  • 1,927 View
  • 32 Download
  • 1 Citations
PDF
Original Articles
Effect of Obesity on Blood Pressure and Arterial Stiffness in Middle-Aged Korean Women
Won-Mok Son, Do-Yeon Kim, You-Sin Kim, Min-Seong Ha
Osong Public Health Res Perspect. 2017;8(6):369-372.   Published online December 31, 2017
DOI: https://doi.org/10.24171/j.phrp.2017.8.6.02
  • 1,995 View
  • 35 Download
  • 7 Citations
AbstractAbstract PDF
Objectives

Our study aims to provide basic scientific data on the importance of obesity management in middle-aged Korean women by analyzing its effects on blood pressure and arterial stiffness. In addition, we examined the correlations of these two parameters.

Methods

The study participants were 40 middle-aged female volunteers, who were classified into obesity group (n = 20) and normal weight group (n = 20). Statistical analysis was performed using independent t-test and the Pearson correlation coefficient was used to correlate blood pressure and arterial stiffness.

Results

This study evaluated the systolic blood pressure, diastolic blood pressure, and pulse wave velocity (PWV). These results were higher in the obesity group than the normal weight group. Furthermore, blood pressure and arterial stiffness (PWV, augmentation pressure) were static correlated.

Conclusion

Obesity is closely related to blood pressure and arterial stiffness. Therefore, indices for blood pressure and arterial stiffness may play a vital role in predicting and preventing obesity and its sequelae.

Effects of Timely Control Intervention on the Spread of Middle East Respiratory Syndrome Coronavirus Infection
Ilsu Choi, Dong Ho Lee, Yongkuk Kim
Osong Public Health Res Perspect. 2017;8(6):373-376.   Published online December 31, 2017
DOI: https://doi.org/10.24171/j.phrp.2017.8.6.03
  • 2,446 View
  • 26 Download
  • 1 Citations
AbstractAbstract PDF
Objectives

The 2015 Middle East Respiratory Syndrome Coronavirus (MERS-CoV) outbreak in Korea caused major economic and social problems. The control intervention was conducted during the MERS-CoV outbreak in Korea immediately after the confirmation of the index case. This study investigates whether the early risk communication with the general public and mass media is an effective preventive strategy.

Methods

The SEIR (Susceptible, Exposed, Infectious, Recovered) model with estimated parameters for the time series data of the daily MERS-CoV incidence in Korea was considered from May to December 2015. For 10,000 stochastic simulations, the SEIR model was computed using the Gillespie algorithm. Depending on the time of control intervention on the 20th, 40th, and 60th days after the identification of the index case, the box plots of MERS-CoV incidences in Korea were computed, and the results were analyzed via ANOVA.

Results

The box plots showed that there was a significant difference between the non-intervention and intervention groups (the 20th day, 40th day, and 60th day groups) and seemed to show no significant difference based on the time of intervention. However, the ANOVA revealed that early intervention was a good strategy to control the disease.

Conclusion

Appropriate risk communication can secure the confidence of the general public in the public health authorities.

Korean Adolescents’ Health Behavior and Psychological Status according to Their Mother’s Nationality
Yunjeong Yi, Ji-Soo Kim
Osong Public Health Res Perspect. 2017;8(6):377-383.   Published online December 31, 2017
DOI: https://doi.org/10.24171/j.phrp.2017.8.6.04
  • 2,195 View
  • 23 Download
  • 4 Citations
AbstractAbstract PDF
Objectives

This study was conducted to compare adolescents’ health behaviors and psychological status according to whether or not their mother was born in Korea.

Methods

This secondary analysis used nationally representative data from the 2015 Korean Youth Risk Behavior Web-based Survey. The self-administered questionnaire included computer measured socio-demographic variables, 15 health behaviors, and psychological status. Data from 65,426 middle school and high school students were analyzed. Multiple logistic regression, adjusting for socio-demographic variables, was used to analyze differences in health behaviors and psychological status between adolescents with a foreign-born mother and those with a Korean mother.

Results

Adolescents who have foreign-born mothers had a lower level of current drinking and subjective happiness, but a higher stress level.

Conclusion

The stress levels of the adolescents with foreign-born mothers could be affected by their multicultural background. It is necessary to analyze stress-influencing factors of multicultural adolescents by comparing them to adolescents from Korean parents. Additionally, our society should pay more attention to the mental health of multicultural adolescents. Schools should also make various efforts to protect multicultural adolescents by adopting mental health management programs led by school nurses and counselors.

Epidemiological Study on Candida Species in Patients with Cancer in the Intensive Care Unit
Young-ju Choi, Byeongyeo Lee, Sun-A Park
Osong Public Health Res Perspect. 2017;8(6):384-388.   Published online December 31, 2017
DOI: https://doi.org/10.24171/j.phrp.2017.8.6.05
  • 2,029 View
  • 22 Download
  • 1 Citations
AbstractAbstract PDF
Objectives

Although cancer survival rates have increased, serious infection complications can arise in cancer patients. Candida can occur in various tissues and has significant effects on the prognosis of patients with cancer. Thus, we conducted an epidemiological study on Candida infections in patients with cancer admitted to the intensive care unit.

Methods

A retrospective study was conducted in adult patients with cancer admitted to the intensive care unit between January 1, 2013, and December 31, 2015. Candida infection status and predictive factors for mortality were examined in 634 patients.

Results

The predictive factors for mortality included the use of steroids, use of a central venous catheter or mechanical ventilator, and identification of Candida in the blood. Patients who stayed in the surgical and intensive care unit for more than 7 days had a lower risk of death than that in those with shorter days.

Conclusion

The present study shows that invasive procedures, bloodstream infections, and the use of steroids increase the risk of mortality in Candida-infected patients with cancer. To improve the quality of life and reduce mortality, further studies are needed on the factors affecting the risk of mortality associated with Candida infection.

Development of a New Approach to Determine the Potency of Bacille Calmette–Guérin Vaccines Using Flow Cytometry
Eunjeong Gweon, Chanwoong Choi, Jaeok Kim, Byungkuk Kim, Hyunkyung Kang, Taejun Park, Sangja Ban, Minseok Bae, Sangjin Park, Jayoung Jeong
Osong Public Health Res Perspect. 2017;8(6):389-396.   Published online December 31, 2017
DOI: https://doi.org/10.24171/j.phrp.2017.8.6.06
  • 2,246 View
  • 20 Download
  • 1 Citations
AbstractAbstract PDF
Objectives

To circumvent the limitations of the current golden standard method, colony-forming unit (CFU) assay, for viability of Bacille Calmette–Guérin (BCG) vaccines, we developed a new method to rapidly and accurately determine the potency of BCG vaccines.

Methods

Based on flow cytometry (FACS) and fluorescein diacetate (FDA) as the most appropriate fluorescent staining reagent, 17 lots of BCG vaccines for percutaneous administration and 5 lots of BCG vaccines for intradermal administration were analyzed in this study. The percentage of viable cells measured by flow cytometry along with the total number of organisms in BCG vaccines, as determined on a cell counter, was used to quantify the number of viable cells.

Results

Pearson correlation coefficients of FACS and CFU assays for percutaneous and intradermal BCG vaccines were 0.6962 and 0.7428, respectively, indicating a high correlation. The coefficient of variation value of the FACS assay was less than 7%, which was 11 times lower than that of the CFU assay.

Conclusion

This study contributes to the evaluation of new potency test method for FACS-based determination of viable cells in BCG vaccines. Accordingly, quality control of BCG vaccines can be significantly improved.

Effects of Anti-Smoking Public Service Announcements on the Attitudes of Korean College Students toward Smoking
Kyoung Won Cho, Jakyoung Lee, Ji-hye Ryu, Soo Jeong Kim
Osong Public Health Res Perspect. 2017;8(6):397-404.   Published online December 31, 2017
DOI: https://doi.org/10.24171/j.phrp.2017.8.6.07
  • 2,385 View
  • 40 Download
  • 3 Citations
AbstractAbstract PDFSupplementary Material
Objectives

This study aimed to identify the effects of anti-smoking public service announcements on the attitudes of Korean college students toward smoking.

Methods

This study involved students via convenience sampling from seven universities who were randomly assigned to four groups. All groups completed a preliminary questionnaire, before being shown a public service announcement twice, and then completed a post viewing questionnaire.

Results

For announcements with positive messages, the proportion of changes in beliefs and attitudes were 39.1% and 19.8%, respectively, whereas those with negative messages showed a greater proportion of changes in the beliefs (59.7%) and attitudes (40.3%). After adjusting for sex and change in belief, the message types and smoking status were identified as factors affecting the change in the participants attitudes. A negative message resulted in a greater change in attitudes (odds ratio [OR], 3.047; 95% confidence interval [CI], 1.847–5.053). Ever-smokers including current smokers showed a greater positive change in attitude than never-smokers (OR, 6.965; 95% CI, 4.107–11.812).

Conclusion

This study found that positive anti-smoking public service announcements were more effective on attitude change than negative messages. Additionally these announcements were more effective among viewers who were current smokers or had a prior smoking experience.

Relationship between Alcohol Purchasing Time and Alcohol Use Disorder in South Korea
Narcie Faith Amista, Sungsoo Chun, Mieun Yun
Osong Public Health Res Perspect. 2017;8(6):405-414.   Published online December 31, 2017
DOI: https://doi.org/10.24171/j.phrp.2017.8.6.08
  • 2,256 View
  • 34 Download
  • 1 Citations
AbstractAbstract PDF
Objectives

Currently, time of alcohol purchase is not part of the policies to regulate alcohol consumption in South Korea. This study was conducted to determine the relationship between alcohol purchasing time and alcohol use disorder.

Methods

The survey for this study was conducted in geographically diverse regions of South Korea in 2012. Respondents’ purchasing behaviors for both on-licensed (i.e., allows for consumption within the premises) and off-licensed (i.e., where alcohol is consumed off the premises) outlets and time of alcohol consumption were collected. Alcohol consumption patterns were examined using the Rapid Alcohol Problem Screen 4 (RAPS4). Data were also analyzed by age, gender and purchasing time.

Results

Results showed that among the off-licensed premises, supermarkets appear to be the most popular venue while for on-licensed premises; alcohol was generally consumed inside hotels/pubs regardless of age and gender of the purchaser. Purchasing of alcohol was highest during the day and early evening period (9:00 a.m. to 9:59 p.m.). Females are most likely to abuse alcohol than males during the early morning period and is that period after 12:00 midnight.

Conclusion

Analysis suggests that the survey instrument used in the International Alcohol Control Study is being used to collect data on alcohol purchasing time consumption; therefore, the potential is there to provide accurate results to contribute appropriate policy responses to reduce alcohol related-harm.

Brief Reports
In Vitro Antiviral Activity of Sakuranetin against Human Rhinovirus 3
Hwa-Jung Choi
Osong Public Health Res Perspect. 2017;8(6):415-420.   Published online December 31, 2017
DOI: https://doi.org/10.24171/j.phrp.2017.8.6.09
  • 1,890 View
  • 26 Download
  • 9 Citations
AbstractAbstract PDF
Objectives

Rhinoviruses (RVs) cause common cold and are associated with exacerbation of chronic inflammatory respiratory diseases. Until now, no clinically effective antiviral chemotherapeutic agents to treat diseases caused by human rhinoviruses (HRVs) have been reported. We assessed the anti-HRV3 activity of sakuranetin isolated from Sorbus commixta Hedl. in human epithelioid carcinoma cervix (HeLa) cells, to evaluate its anti-rhinoviral potential in the clinical setting.

Methods

Antiviral activity and cytotoxicity as well as the effect of sakuranetin on HRV3-induced cytopathic effects (CPEs) were evaluated using the sulforhodamine B (SRB) method using CPE reduction. The morphology of HRV3-infected cells was studied using a light microscope.

Results

Sakuranetin actively inhibited HRV3 replication and exhibited antiviral activity of more than 67% without cytotoxicity in HeLa cells, at 100 μg/mL. Ribavirin showed anti-HRV3 activity similar to that of sakuranetin. Treatment of HRV-infected HeLa cells with sakuranetin visibly reduced CPEs.

Conclusion

The inhibition of HRV production by sakuranetin is mainly due to its general antioxidant activity through inhibition of viral adsorption. Therefore, the antiviral activity of sakuranetin should be further investigated to elucidate its mode of action and prevent HRV3-mediated diseases in pathological conditions.

Follow-up Study of Patients Previously Diagnosed with Lymphatic Filariasis in Korea
Hyeng Il Cheun, Hee Eun Shin, Da Won Ma, Sung Hee Hong, Tae Yun Kim, Sang Eun Lee, JungWon Ju, Yun-Kyu Park, Tong-Soo Kim, Shin Hyeong Cho
Osong Public Health Res Perspect. 2017;8(6):421-424.   Published online December 31, 2017
DOI: https://doi.org/10.24171/j.phrp.2017.8.6.10
  • 1,955 View
  • 20 Download
  • 2 Citations
AbstractAbstract PDF
Objectives

Korea was an endemic area for lymphatic filariasis (LF), caused by the nematode parasite Brugia malayi, until the 1970s. The World Health Organization recognized Korea as LF-free in June 2008. However, it is necessary to confirm that patients that have had LF in the past still test negative, to prevent the re-emergence of LF in Korea.

Methods

We followed up a total of 83 patients who had been diagnosed with LF between 2002 and 2010 in endemic LF areas.

Results

Fifty-two of the 83 subjects were negative for LF, whereas 31 subjects had re-located to a different city or province, were dead, or were unaccounted for. Most subjects with negative test results still exhibited edema in the legs or the arms, and some complained of redness and swelling in the legs or ankle joints. However, we found that these symptoms were due to diseases other than LF.

Conclusion

In this follow-up study, we did not find any evidence indicating the potential re-emergence of LF in Korea.


PHRP : Osong Public Health and Research Perspectives