<sec>
<title>Objectives</title>
<p>Menopause is a well-known risk factor for accelerating cognitive aging in women. This study aimed to assess differences in cognitive function and health-related quality of life (HRQOL) according to menopausal status to determine whether the menopause significantly affects the relationship between cognitive function and HRQOL.</p></sec>
<sec>
<title>Methods</title>
<p>This was a cross-sectional comparative study with a convenience sample of 178 Korean women including 89 naturally menopausal women (65 ± 10 years) and 89 non-menopausal women (45 ± 8 years) who met the eligibility criteria and completed neuropsychological tests and self-report questionnaires about their HRQOL, cognitive function, depression, and sleep quality. Multiple regression analyses were performed within and between groups according to menopausal status.</p></sec>
<sec>
<title>Results</title>
<p>Menopausal women had significantly worse scores on neuropsychological performance and HRQOL than non-menopausal women. A better neuropsychological performance (β = 0.34) was solely associated with a better HRQOL in menopausal women, whilst socioeconomic variables were associated with HRQOL in non-menopausal women.</p></sec>
<sec>
<title>Conclusion</title>
<p>Menopause is an important risk factor for HRQOL, and the association between cognition and HRQOL may differ according to menopausal status. When developing programs for target groups to improve daily functioning and HRQOL, healthcare professionals need to pay more attention to this relationship.</p></sec>
Citations
Citations to this article as recorded by
Impact of sleep disturbances on health-related quality of life in postmenopausal women: a systematic review Claudio N. Soares, Malek Bajbouj, Nils Schoof, Amit Kishore, Cecilia Caetano Menopause.2026; 33(1): 118. CrossRef
Assessing the Relationship Between Depressive Symptoms and Menopausal Quality of Life Among Academic Women in Saudi Arabia Sally Mohammed Farghaly Abdelaliem, Noha Mohamed Mahmoud Hassan, Aljory Alqahtani, Lama Alamer, Noura Alhomaid, Hessa Alsubaie, Rania Alsaeed, Dalal Al-Qahtani, Mudhawi Alenazi Healthcare.2025; 13(13): 1557. CrossRef
Brain volumetric changes in menopausal women and its association with cognitive function: a structured review Nur Zuliani Ramli, Mohamad Fairuz Yahaya, Nur Azlina Mohd Fahami, Hanani Abdul Manan, Meharvan Singh, Hanafi Ahmad Damanhuri Frontiers in Aging Neuroscience.2023;[Epub] CrossRef
<sec>
<title>Objectives</title>
<p>Self-rated health is a comprehensive measure of health. As gender difference in self-rated health is found, identifying gender-specific factors related to self-rated health is important. Poor executive functioning negatively affects an individual’s independence and healthy lifestyle, but it is unknown relationships between executive function and self-rated health and gender differences in these relationships. Therefore, gender differences were examined in the relationship between executive function and self-rated health in the community.</p></sec>
<sec>
<title>Methods</title>
<p>Individuals completed questionnaires about their health status and subjective decline in executive function. Neuropsychological tests were also performed to assess objective executive functioning. Two separate multivariable linear regression analyses were conducted by gender.</p></sec>
<sec>
<title>Results</title>
<p>Better objective executive function was related to greater self-rated health scores (better self-rated health) in men alone (βs = 0.341), while better subjective executive function was significantly associated with greater self-rated health scores in both men and women (βs = 0.385 and 0.443, respectively).</p></sec>
<sec>
<title>Conclusion</title>
<p>Gender differences are important when reporting perceived health status, in particular the different effects of subjective and objective executive function on self-rated health across genders. Clinicians need to be aware of the potential value of subjective executive function complaints when evaluating health status.</p></sec>
Citations
Citations to this article as recorded by
The Scale Assessment of Executive Functions-Adult (SAEF-A): Construction of a valid ecological instrument Farah El houari, Ibtissam El Harch, Abdelkrim Janati Idrissi, Samira El fakir, Benaissa Zarhbouch, Zouhayr Souirti Applied Neuropsychology: Adult.2025; 32(6): 1654. CrossRef
Psychometric properties of the Teenage Executive Functioning Inventory (TEXI): A confirmatory factor analysis and measurement invariance by gender in Bangladeshi adolescents Bijon Baroi, Samsad Afrin Himi Applied Neuropsychology: Child.2025; 14(4): 422. CrossRef
Screen time exposure and executive functions in preschool children Nemanja Lakicevic, Marko Manojlovic, Elena Chichinina, Patrik Drid, Yury Zinchenko Scientific Reports.2025;[Epub] CrossRef
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The complex relationship between treatment burden of multimorbidity and self-care in multimorbid patients with hypertension Kyoung Suk Lee, Jihyang Lee BMC Primary Care.2025;[Epub] CrossRef
Self-rated flexibility significantly reflects the hip flexibility, but not the ankle flexibility Wootaek Lim Isokinetics and Exercise Science.2024; 32(2): 171. CrossRef
Educational Attainment and Perceived Need for Future ADL Assistance Julia M. Finan, Scott D. Landes Journal of Applied Gerontology.2024; 43(7): 922. CrossRef
The impact of epidemic infectious diseases on the relationship between subjective well-being and social class identity in older adults: The mediating role of Self-rated health Qianxi Feng, Yan Li, Miao Wan, Wei Li, Roghieh Nooripour PLOS ONE.2024; 19(3): e0301289. CrossRef
Current state, equality level and trends of self-rated health among old adults with intact physical condition Weicun Ren, Clifford Silver Tarimo, Zhang Liang BMC Public Health.2023;[Epub] CrossRef
Gender features of awareness and attitude towards a healthy lifestyle among users of medical Internet resources A.N. Korobeynikova, M.V. Bezzubtseva, A.E. Demkina, A.D. Yuldasheva, S.V. Popova, A.L. Pivenshtein, A.V. Isaeva, V.G. Starosvetskaya, Z.G. Akaeva, E.L. Kolesnik Russian Journal of Preventive Medicine.2023; 26(10): 62. CrossRef
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Association between Hippocampal Volume and Working Memory in 10,000+ 9–10-Year-Old Children: Sex Differences Shervin Assari, Shanika Boyce, Tanja Jovanovic Children.2021; 8(5): 411. CrossRef
Social Capital and Self-Rated Health: Empirical Evidence from China Jiafeng Gu, Ruiyu Zhu International Journal of Environmental Research an.2020; 17(23): 9108. CrossRef
Effect of self-rated health status on functioning difficulties among older adults in Ghana: Coarsened exact matching method of analysis of the World Health Organization’s study on global AGEing and adult health, Wave 2 John Tetteh, Robert Kogi, Anita Ohenewa Yawson, George Mensah, Richard Biritwum, Alfred Edwin Yawson, Heidi H. Ewen PLOS ONE.2019; 14(11): e0224327. CrossRef
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