Osong Public Health and Research Perspectives

Original Articles

Quality of Life of Chronic Hepatitis C Patients and Its Associated Factors: Hoo Jeung Cho, Euna Park; Osong Public Health Res Perspect. 2017;8(2):124-129. Published online April 30, 2017; DOI: https://doi.org/10.24171/j.phrp.2017.8.2.04

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Objectives

This study aimed to investigate the factors affecting the health-related quality of life (HRQOL) of patients with chronic hepatitis C (CHC).

Methods

This study is based on a descriptive survey and involved 125 gastroenterology outpatients visiting a university hospital in South Korea as the participants. HRQOL was assessed using the Liver Disease Quality of Life 1.0, which consisted of Short Form-36 (SF-36) and the Liver Disease Targeted Scale. Data were collected from December 2015 to April 2016, which were then analyzed through multiple regression analysis.

Results

HRQOL had a statistically significant correlation with age, sex, educational level, living type, employment status, monthly income level, and comorbidity status. This study showed that age > 51 years, female sex, high educational level, living alone, unemployment status, low monthly income, and presence of comorbidity had negative effects on the HRQOL of patients with CHC (R² = 8.7%–34.6%).

Conclusion

Based on the result of this study, intervention for patients with CHC needs to be developed to enhance their HRQOL. The findings can serve as a useful reference for nursing personnel in the development of therapeutic plans to upgrade the care of CHC patients.

Citations

Citations to this article as recorded by

Clinical and individual factors of quality of life of chronic liver disease patients at University of Gondar comprehensive specialized hospital, Northwest Ethiopia 2022
Eliud Teshome, Workagegnehu Hailu, Aynishet Adane, Endalkachew Belayneh Melese, Dessie Abebaw Angaw, Gebrekidan Ewnetu Tarekegn
Medicine.2023; 102(45): e35425. CrossRef
Risk factors of severe hepatotoxicity among HIV-1 infected individuals initiated on highly active antiretroviral therapy in the Northwest Region of Cameroon
Lem Edith Abongwa, Anthony Kebira Nyamache, Fokunang Charles, Judith Torimiro, Nshom Emmanuel, Irénée Domkam, Mbu Eyongetah, Beriyuy Jude, Fung Holgar Mua, Sama Bella, Tankou Colman Tamboh, Erna Charlene Moungang, Victorine Ngum, Paul Okemo
BMC Gastroenterology.2022;[Epub] CrossRef
Cathepsin B and Plasma Kallikrein Are Reliable Biomarkers to Discriminate Clinically Significant Hepatic Fibrosis in Patients with Chronic Hepatitis-C Infection
Alexia de Cassia Oliveira Zanelatto, Gilmar de Souza Lacerda, Camila de Melo Accardo, Natalia Fonseca do Rosário, Andréa Alice da Silva, Guacyara Motta, Ivarne Luis dos Santos Tersariol, Analucia Rampazzo Xavier
Microorganisms.2022; 10(9): 1769. CrossRef
Impact of newer direct-acting antiviral drugs based on quality-adjusted life years: A prospective pharmacoeconomic study in hepatitis C patients
BhavyaH Vyas, NishitaH Darji, DevangA Rana, KaushalY Vyas, SupriyaD Malhotra
Perspectives in Clinical Research.2021; 12(2): 76. CrossRef
Exploring Perception of Chronic Hepatitis C: An Idiographic Case Study
Hana Arshad, Subha Malik
Pakistan Journal of Psychological Research.2020; 34(4): 735. CrossRef
Changes in Quality of Life of Chronic Hepatitis C Patients Participating in Clinical Trial
Hoo-Jeung CHO, Euna PARK
JOURNAL OF FISHRIES AND MARINE SCIENCES EDUCATION.2018; 30(5): 1725. CrossRef
Treatment with Sofosbuvir and Daclatasvir (with or without Ribavirin) Improves Patient Reported Outcomes in Hepatitis C
Lucas Pereira Jorge de Medeiros, Mario Barreto Correa Lima, Marcia Maria Amêndola Pires, Alessandra Mendonça Almeida Maciel, Renata Barboza Vianna Medeiros, Mariana Dermínio Donadel, Isabela Martins Becattini Pereira, Fábio Marchon Leão, Luiz Eduardo Amor
Osong Public Health and Research Perspectives.2018; 9(2): 50. CrossRef
Quality of life in Brazilian patients with treated or untreated chronic hepatitis C
Cássio Marques Perlin, Vinicius Lins Ferreira, Helena Hiemisch Lobo Borba, Astrid Wiens, Cláudia Alexandra Pontes Ivantes, Luana Lenzi, Roberto Pontarolo
Revista do Instituto de Medicina Tropical de São P.2017;[Epub] CrossRef

Illness Experience of Patients with Chronic Hepatitis C Participating in Clinical Trials: Hoo-Jeung Cho, Euna Park; Osong Public Health Res Perspect. 2016;7(6):394-399. Published online December 31, 2016; DOI: https://doi.org/10.1016/j.phrp.2016.11.001

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19 Download
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Abstract PDF

Objectives
To understand the illness experience of patients with chronic hepatitis C participating in clinical trials in the sociocultural context of Korea in an in-depth and comprehensive manner.
Methods
A focused ethnography approach was used to discover the pattern of illness experience of patients with chronic hepatitis C in the cultural background of Korea. Interviews were conducted with 11 patients with chronic hepatitis C participating in clinical trials and the collected data were analyzed with the domain analysis, taxonomical analysis, componential analysis, and theme analysis proposed by Spradley.
Results
With the cultural theme of “less-known illness, less-familiar illness,” four categories were derived: “my illness discovered by accident,” “shaken life,” “scary but inevitable treatment method,” and “precious life that can't be wasted,” along with 12 properties.
Conclusion
Public campaigns or education programs are needed to meet the needs for information on the disease for patients with chronic hepatitis C participating in clinical trials and help the general public acquire knowledge or change view on this disease.

Citations

Citations to this article as recorded by

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Gayatri Marathe, Erica E M Moodie, Marie-Josée Brouillette, Charlotte Lanièce Delaunay, Joseph Cox, Valérie Martel-Laferrière, John Gill, Curtis Cooper, Neora Pick, Marie-Louise Vachon, Sharon Walmsley, Marina B Klein, Lisa Barrett, Jeff Cohen, Brian Conw
Clinical Infectious Diseases.2023; 76(3): e702. CrossRef
“There are many fevers”: Communities’ perception and management of Febrile illness and its relationship with human animal interactions in South-Western Uganda
Michael Wandanje Mahero, Katherine M. Pelican, Jacinta M. Waila, Shamilah Namusisi, Innocent B. Rwego, Charles Kajura, Christopher Nyatuna, David R. Boulware, Joel Hartter, Lawrence Mugisha, Cheryl Robertson, Dominic A. Travis, Kate Zinszer
PLOS Neglected Tropical Diseases.2022; 16(2): e0010125. CrossRef
Effect of Disease-related Knowledge and Health Enhancement Lifestyle on Self-management Behavior among Chronic Hepatitis C Patients
Hoo Jeung CHO, Euna PARK
THE JOURNAL OF FISHERIES AND MARINE SCIENCES EDUCA.2022; 34(2): 219. CrossRef
Assessing potential cures: are there distinctive elements of value beyond health gain?
Saskia Hendriks, Steven D Pearson
Journal of Comparative Effectiveness Research.2021; 10(4): 255. CrossRef
Depression in patients with chronic hepatitis-C treated with direct-acting antivirals: A real-world prospective observational study
Mohamed A. Khalil, Hend Ibrahim Shousha, Saeed M. El-Nahaas, Mohamed Ibrahim Negm, Kariman Kamal, Nagwan Mohamed Madbouly
Journal of Affective Disorders.2021; 282: 126. CrossRef

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