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2 "chronic hepatitis C"
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Quality of Life of Chronic Hepatitis C Patients and Its Associated Factors
Hoo Jeung Cho, Euna Park
Osong Public Health Res Perspect. 2017;8(2):124-129.   Published online April 30, 2017
  • 4,882 View
  • 33 Download
  • 8 Crossref
AbstractAbstract PDF

This study aimed to investigate the factors affecting the health-related quality of life (HRQOL) of patients with chronic hepatitis C (CHC).


This study is based on a descriptive survey and involved 125 gastroenterology outpatients visiting a university hospital in South Korea as the participants. HRQOL was assessed using the Liver Disease Quality of Life 1.0, which consisted of Short Form-36 (SF-36) and the Liver Disease Targeted Scale. Data were collected from December 2015 to April 2016, which were then analyzed through multiple regression analysis.


HRQOL had a statistically significant correlation with age, sex, educational level, living type, employment status, monthly income level, and comorbidity status. This study showed that age > 51 years, female sex, high educational level, living alone, unemployment status, low monthly income, and presence of comorbidity had negative effects on the HRQOL of patients with CHC (R2 = 8.7%–34.6%).


Based on the result of this study, intervention for patients with CHC needs to be developed to enhance their HRQOL. The findings can serve as a useful reference for nursing personnel in the development of therapeutic plans to upgrade the care of CHC patients.


Citations to this article as recorded by  
  • Clinical and individual factors of quality of life of chronic liver disease patients at University of Gondar comprehensive specialized hospital, Northwest Ethiopia 2022
    Eliud Teshome, Workagegnehu Hailu, Aynishet Adane, Endalkachew Belayneh Melese, Dessie Abebaw Angaw, Gebrekidan Ewnetu Tarekegn
    Medicine.2023; 102(45): e35425.     CrossRef
  • Risk factors of severe hepatotoxicity among HIV-1 infected individuals initiated on highly active antiretroviral therapy in the Northwest Region of Cameroon
    Lem Edith Abongwa, Anthony Kebira Nyamache, Fokunang Charles, Judith Torimiro, Nshom Emmanuel, Irénée Domkam, Mbu Eyongetah, Beriyuy Jude, Fung Holgar Mua, Sama Bella, Tankou Colman Tamboh, Erna Charlene Moungang, Victorine Ngum, Paul Okemo
    BMC Gastroenterology.2022;[Epub]     CrossRef
  • Cathepsin B and Plasma Kallikrein Are Reliable Biomarkers to Discriminate Clinically Significant Hepatic Fibrosis in Patients with Chronic Hepatitis-C Infection
    Alexia de Cassia Oliveira Zanelatto, Gilmar de Souza Lacerda, Camila de Melo Accardo, Natalia Fonseca do Rosário, Andréa Alice da Silva, Guacyara Motta, Ivarne Luis dos Santos Tersariol, Analucia Rampazzo Xavier
    Microorganisms.2022; 10(9): 1769.     CrossRef
  • Impact of newer direct-acting antiviral drugs based on quality-adjusted life years: A prospective pharmacoeconomic study in hepatitis C patients
    BhavyaH Vyas, NishitaH Darji, DevangA Rana, KaushalY Vyas, SupriyaD Malhotra
    Perspectives in Clinical Research.2021; 12(2): 76.     CrossRef
  • Exploring Perception of Chronic Hepatitis C: An Idiographic Case Study
    Hana Arshad, Subha Malik
    Pakistan Journal of Psychological Research.2020; 34(4): 735.     CrossRef
  • Changes in Quality of Life of Chronic Hepatitis C Patients Participating in Clinical Trial
    Hoo-Jeung CHO, Euna PARK
  • Treatment with Sofosbuvir and Daclatasvir (with or without Ribavirin) Improves Patient Reported Outcomes in Hepatitis C
    Lucas Pereira Jorge de Medeiros, Mario Barreto Correa Lima, Marcia Maria Amêndola Pires, Alessandra Mendonça Almeida Maciel, Renata Barboza Vianna Medeiros, Mariana Dermínio Donadel, Isabela Martins Becattini Pereira, Fábio Marchon Leão, Luiz Eduardo Amor
    Osong Public Health and Research Perspectives.2018; 9(2): 50.     CrossRef
  • Quality of life in Brazilian patients with treated or untreated chronic hepatitis C
    Cássio Marques Perlin, Vinicius Lins Ferreira, Helena Hiemisch Lobo Borba, Astrid Wiens, Cláudia Alexandra Pontes Ivantes, Luana Lenzi, Roberto Pontarolo
    Revista do Instituto de Medicina Tropical de São P.2017;[Epub]     CrossRef
Illness Experience of Patients with Chronic Hepatitis C Participating in Clinical Trials
Hoo-Jeung Cho, Euna Park
Osong Public Health Res Perspect. 2016;7(6):394-399.   Published online December 31, 2016
  • 3,330 View
  • 21 Download
  • 5 Crossref
AbstractAbstract PDF
To understand the illness experience of patients with chronic hepatitis C participating in clinical trials in the sociocultural context of Korea in an in-depth and comprehensive manner.
A focused ethnography approach was used to discover the pattern of illness experience of patients with chronic hepatitis C in the cultural background of Korea. Interviews were conducted with 11 patients with chronic hepatitis C participating in clinical trials and the collected data were analyzed with the domain analysis, taxonomical analysis, componential analysis, and theme analysis proposed by Spradley.
With the cultural theme of “less-known illness, less-familiar illness,” four categories were derived: “my illness discovered by accident,” “shaken life,” “scary but inevitable treatment method,” and “precious life that can't be wasted,” along with 12 properties.
Public campaigns or education programs are needed to meet the needs for information on the disease for patients with chronic hepatitis C participating in clinical trials and help the general public acquire knowledge or change view on this disease.


Citations to this article as recorded by  
  • Impact of Hepatitis C Virus Cure on Depressive Symptoms in the Human Immunodeficiency Virus-Hepatitis C Virus Coinfected Population in Canada
    Gayatri Marathe, Erica E M Moodie, Marie-Josée Brouillette, Charlotte Lanièce Delaunay, Joseph Cox, Valérie Martel-Laferrière, John Gill, Curtis Cooper, Neora Pick, Marie-Louise Vachon, Sharon Walmsley, Marina B Klein, Lisa Barrett, Jeff Cohen, Brian Conw
    Clinical Infectious Diseases.2023; 76(3): e702.     CrossRef
  • “There are many fevers”: Communities’ perception and management of Febrile illness and its relationship with human animal interactions in South-Western Uganda
    Michael Wandanje Mahero, Katherine M. Pelican, Jacinta M. Waila, Shamilah Namusisi, Innocent B. Rwego, Charles Kajura, Christopher Nyatuna, David R. Boulware, Joel Hartter, Lawrence Mugisha, Cheryl Robertson, Dominic A. Travis, Kate Zinszer
    PLOS Neglected Tropical Diseases.2022; 16(2): e0010125.     CrossRef
  • Effect of Disease-related Knowledge and Health Enhancement Lifestyle on Self-management Behavior among Chronic Hepatitis C Patients
    Hoo Jeung CHO, Euna PARK
  • Assessing potential cures: are there distinctive elements of value beyond health gain?
    Saskia Hendriks, Steven D Pearson
    Journal of Comparative Effectiveness Research.2021; 10(4): 255.     CrossRef
  • Depression in patients with chronic hepatitis-C treated with direct-acting antivirals: A real-world prospective observational study
    Mohamed A. Khalil, Hend Ibrahim Shousha, Saeed M. El-Nahaas, Mohamed Ibrahim Negm, Kariman Kamal, Nagwan Mohamed Madbouly
    Journal of Affective Disorders.2021; 282: 126.     CrossRef

PHRP : Osong Public Health and Research Perspectives