Osong Public Health and Research Perspectives

Review Article

The contribution of dietary total antioxidant capacity to type 2 diabetes risk and levels of glycemic biomarkers: a systematic review: Sorayya Kheirouri, Hamed Alizadeh; Received December 10, 2024 Accepted February 24, 2025 Published online March 27, 2025; DOI: https://doi.org/10.24171/j.phrp.2024.0337 [Epub ahead of print]

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Abstract PDF Supplementary Material: Objectives
This study systematically reviewed and analyzed epidemiological evidence regarding the association between dietary total antioxidant capacity (DTAC) and both the risk of developing diabetes and glycemic biomarker levels.
Methods
We searched the PubMed, Scopus, ScienceDirect, and Google Scholar databases through July 2024 without imposing any date restrictions. Original studies that examined the relationship between DTAC and either the risk of developing diabetes or glycemic biomarker levels—specifically fasting blood glucose (FBG), hemoglobin A1C (HbA1C), insulin, and the homeostatic model assessment for insulin resistance (HOMA-IR)—were eligible for inclusion. After eliminating duplicates and irrelevant records, relevant studies were selected, and data were extracted through rigorous critical analysis.
Results
A total of 32 articles were included in the review. Of the 19 studies that evaluated diabetes risk, 15 reported a lower risk among subjects with higher DTAC values. All 4 studies examining prediabetes risk found lower risk in participants with high DTAC scores. Additionally, significant inverse relationships were observed between DTAC values and FBG (9/15 studies), HbA1C (1/6 studies), insulin (5/6 studies), and HOMA-IR (8/9 studies).
Conclusion
The majority of evidence indicates that high adherence to an antioxidant-rich diet may reduce diabetes risk and improve glycemic biomarkers, including FBG, insulin, and HOMA-IR.

Original Articles

Periodontitis and non-communicable diseases in a Brazilian population, a cross-sectional study, Vila Velha-ES, Brazil: Gustavo Vital de Mendonça, Crispim Cerutti Junior, Alfredo Carlos Rodrigues Feitosa, Brígida Franco Sampaio de Mendonça, Lucia Helena Sagrillo Pimassoni; Osong Public Health Res Perspect. 2024;15(3):212-220. Published online June 27, 2024; DOI: https://doi.org/10.24171/j.phrp.2024.0021

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The objective of this study was to examine the hypothesis that periodontal disease is associated with chronic non-communicable diseases. Methods: In this cross-sectional study, we evaluated the periodontal health condition of the population, based on the community periodontal index, as well as the number of missing teeth and the presence of systemic health conditions. We quantified the association between oral health and the presence of chronic diseases using simple logistic regression, adjusting for confounding factors including age, smoking, and overweight. Results: The study population consisted of 334 volunteers, aged between 19 and 81 years. In patients over 45 years old, periodontal disease was found to be significantly associated with hypertension and diabetes. Furthermore, in female patients, periodontal disease was significantly associated with hypertension, diabetes, and cancer. Conclusion: Our findings indicate that periodontal disease is positively and significantly associated with both arterial hypertension and diabetes, independent of potential confounding factors.

Estimation of the onset time of diabetic complications in type 2 diabetes patients in Thailand: a survival analysis: Natthanicha Sauenram, Jutatip Sillabutra, Chukiat Viwatwongkasem, Pratana Satitvipawee; Osong Public Health Res Perspect. 2023;14(6):508-519. Published online November 23, 2023; DOI: https://doi.org/10.24171/j.phrp.2023.0084

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This study aimed to identify factors associated with the onset time of diabetic complications in patients with type 2 diabetes mellitus (T2DM) and determine the best-fitted survival model. Methods: A retrospective cohort study was conducted among T2DM patients enrolled from October 1, 2016 to July 15, 2020 at the National Health Security Office (NHSO). In total, 388 T2DM patients were included. Cox proportional-hazard and parametric models were used to identify factors related to the onset time of diabetic complications. The Akaike information criterion, Bayesian information criterion, and Cox-Snell residual were compared to determine the best-fitted survival model. Results: Thirty diabetic complication events were detected among the 388 patients (7.7%). A 90% survival rate for the onset time of diabetic complications was found at 33 months after the first T2DM diagnosis. According to multivariate analysis, a duration of T2DM ≥42 months (time ratio [TR], 0.56; 95% confidence interval [CI], 0.33–0.96; p=0.034), comorbid hypertension (TR, 0.30; 95% CI, 0.15–0.60; p=0.001), mildly to moderately reduced levels of the estimated glomerular filtration rate (eGFR) (TR, 0.43; 95% CI, 0.24–0.75; p=0.003) and an eGFR that was severely reduced or indicative of kidney failure (TR, 0.38; 95% CI, 0.16–0.88; p=0.025) were significantly associated with the onset time of diabetic complications (p<0.05). Conclusion: Patients with T2DM durations of more than 42 months, comorbid hypertension, and decreased eGFR were at risk of developing diabetic complications. The NHSO should be aware of these factors to establish a policy to prevent diabetic complications after the diagnosis of T2DM.

The risk associated with psychiatric disturbances in patients with diabetes in Indonesia (2018): a cross-sectional observational study: Siti Isfandari, Betty Roosihermiatie, Sulistyowati Tuminah, Laurentia Konadi Mihardja; Osong Public Health Res Perspect. 2023;14(5):368-378. Published online October 18, 2023; DOI: https://doi.org/10.24171/j.phrp.2023.0144; Correction in: Osong Public Health Res Perspect 2023;14(6):530

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Objectives
The global prevalence of psychiatric disturbances is rising, detrimentally affecting the quality of care and treatment outcomes for individuals, particularly those with diabetes.This study investigated the association of risk factors for psychiatric disturbances among productive-age patients with diabetes (ages 30−59 years), considering sociodemographic characteristics and co-existing diseases. The risk factors considered included sociodemographic factors (e.g., residence, age, sex, marital status, education, and occupation) and co-existing diseases (e.g., hypertension, heart disease, stroke, renal failure, rheumatism, asthma, and cancer). Methods: This cross-sectional study utilized data from the 2018 Indonesian National Health Survey (Riskesdas). The study population comprised respondents aged between 30 and 59 years who had diabetes and had completed the 20-question self-reporting questionnaire (SRQ-20). After the exclusion of incomplete SRQ-20 data, the sample included 8,917 respondents. Data were analyzed using logistic regression. Results: Approximately 18.29% of individuals with diabetes displayed symptoms indicative of psychiatric disturbances. After adjusting for sociodemographic factors such as age, sex, education level, occupation, marital status, and place of residence, patients with diabetes who had co-existing conditions such as hypertension, heart diseases, rheumatic disorders, asthma, or cancer had a higher risk for developing psychiatric disturbances than those with diabetes alone (adjusted odds ratio, 6.67; 95% confidence interval, 4.481−9.928; p<0.001). Conclusion: The elevated risk of psychiatric disturbances among patients with diabetes who had comorbidities underscores the importance of addressing mental health issues in the management of diabetes, especially in patients with concurrent disease conditions.

Citations

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Investigating the association between physical fitness and blood pressure among healthcare workers in Indonesia
Wahyu Sulistiadi, Riswandy Wasir, Astriana, Badra Al Aufa, Sri Rahayu, Wasir Thalib, Fadilah Aulia Rahma
Discover Social Science and Health.2024;[Epub] CrossRef
Correction to “The risk associated with psychiatric disturbances in patients with diabetes in Indonesia (2018): a cross-sectional observational study” [Osong Public Health Res Perspect 2023;14(5):368–78]
Siti Isfandari, Betty Roosihermiatie, Sulistyowati Tuminah, Laurentia Konadi Mihardja
Osong Public Health and Research Perspectives.2023; 14(6): 530. CrossRef

Chronic kidney disease in Indonesia: evidence from a national health survey: Puti Sari Hidayangsih, Dwi Hapsari Tjandrarini, Noor Edi Widya Sukoco, Nikson Sitorus, Ika Dharmayanti, Feri Ahmadi; Osong Public Health Res Perspect. 2023;14(1):23-30. Published online February 14, 2023; DOI: https://doi.org/10.24171/j.phrp.2022.0290

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Objectives
Several previous studies have stated that consuming certain foods and beverages might increase the risk of chronic kidney disease (CKD). This study aimed to examine the relationships of food and beverage consumption with other risk factors for CKD. Methods: Data sources included the 2018 Basic Health Research (Riskesdas) and the National Socio-Economic Survey (Susenas), which were analyzed using a cross-sectional design. The study samples were households from 34 provinces in Indonesia, and the analysis was performed with provincial aggregates. Data were analyzed using risk factor analysis followed by linear regression to identify relationships with CKD. Results: The prevalence of CKD in Indonesia was 0.38%. The province with the highest prevalence was North Kalimantan (0.64%), while the lowest was found in West Sulawesi (0.18%). Five major groups were formed from 15 identified risk factors using factor analysis. A linear regression model presented 1 significant selected factor (p=0.006, R2 =31%). The final model of risk factors included water quality, consumption of fatty foods, and a history of diabetes. Conclusion: Drinking water quality, fatty food consumption, and diabetes are associated with CKD. There is a need to monitor drinking water, as well as to promote health education and provide comprehensive services for people with diabetes, to prevent CKD.

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Enhanced detection of albumin-creatinine ratio in urine using gold nanoparticle-integrated 3D-connector microfluidic paper-based analytical devices for early diagnosis of chronic kidney disease
Akhmad Sabarudin, Saidun Fiddaroini, Ahmad Luthfi Fahmi, Abdul Munir Roja’i, Isadora Evani Salsabila, Aulanni’am, Setyawan Purnomo Sakti, Hani Susianti
Microchemical Journal.2025; 211: 113071. CrossRef

Insufficient weight management in pregnant women with gestational diabetes mellitus: Kyunghee Han, Dong Wook Kwak, Hyun Mee Ryu, Hyun-Young Park; Osong Public Health Res Perspect. 2022;13(4):242-251. Published online August 31, 2022; DOI: https://doi.org/10.24171/j.phrp.2022.0182

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Objectives
This study investigated whether weight was managed appropriately in pregnant women with gestational diabetes mellitus (GDM) and examined the association between insufficient gestational weight gain (GWG) and adverse pregnancy outcomes.
Methods
The study included 235 pregnant women with GDM from the Korean Pregnancy Outcome Study. GWG from the second to the third trimester (kg/wk) and total GWG (kg) were classified as insufficient, appropriate, or excessive according to the 2009 Institute of Medicine guidelines. Adverse pregnancy outcomes included maternal (hypertensive disorders of pregnancy, preterm birth, cesarean delivery, and delivery complications) and infant (low birth weight, high birth weight, neonatal intensive care unit admission, and congenital anomalies) outcomes.
Results
The proportion of pregnant women with GDM who had insufficient GWG from the second to the third trimester was 52.3%, and that of participants with total insufficient GWG was 48.1%. There were no significant associations between insufficient GWG from the second to the third trimester and adverse pregnancy outcomes. Participants with total insufficient GWG had a significantly lower risk of preterm birth (odds ratio [OR], 0.17; 95% confidence interval [CI], 0.05–0.60) and high birth weight (OR, 0.23; 95% CI, 0.07–0.80).
Conclusion
Our findings suggest the importance of appropriate weight management and the need for GWG guidelines for pregnant women with GDM.

Citations

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Risk factors and prediction model for low-birth-weight infants born to women with gestational diabetes mellitus
Yu-qing Pan, Xin-xin Huang, Xiu-min Jiang
Frontiers in Public Health.2024;[Epub] CrossRef

Educational Needs Associated with the Level of Complication and Comparative Risk Perceptions in People with Type 2 Diabetes: Youngji Hwang, Dongsuk Lee, Yeon Sook Kim; Osong Public Health Res Perspect. 2020;11(4):170-176. Published online August 31, 2020; DOI: https://doi.org/10.24171/j.phrp.2020.11.4.05

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Abstract PDF

Objectives

This study aimed to identify the educational needs of people with type 2 diabetes according to risk perceptions and the level of severity of complications.

Methods

There were 177 study participants who were outpatients of the internal medicine department at a university hospital located in the Republic of Korea, who consented to participate in the survey from December 10, 2016 to February 10, 2017. The data were analyzed using descriptive statistics, Pearson correlation, ANOVA with post-hoc comparison, and multiple regression analysis. Type 2 diabetes complications were classified into 3 groups: no complications, common complications, and severe complications.

Results

There were statistically significant positive correlations between educational needs and comparative risk perceptions, and the level of complication and comparative risk perception. Multiple regression analysis revealed that the factor predicting educational needs of type 2 diabetes people was their comparative risk perceptions, rather than the severity of diabetes complications or sociodemographic variables.

Conclusion

Since risk perception is the factor that indicates the educational needs of people with type 2 diabetes, there is a need to explore factors which increase risk perception, in order to meet educational needs. The findings suggest that a more specific and individualized educational program, which focuses on each person's risk perceptions, should be developed.

Citations

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Determinants of Complications of Diabetic Among Adult with Type 2 Diabetic Patients at Hubaal Specialist Hospital and Libaan Hospital in Mogadishu: Case Control Study
Ahmed Mohamed, Ali Mohamed, Ahmed Guled, Mohamed Fuji, Abdullahi Qoryoley, Abdirahman Hassan
American Journal of Internal Medicine.2024; 12(5): 82. CrossRef

The Association Between Lung Function and Type 2 Diabetes in Koreans: Do-Youn Lee, Seung-min Nam; Osong Public Health Res Perspect. 2020;11(1):27-33. Published online February 28, 2020; DOI: https://doi.org/10.24171/j.phrp.2020.11.1.05

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Abstract PDF

Objectives

This study was performed to test the association between lung function and type 2 diabetes mellitus (T2DM) in Korean patients.

Methods

Data from the 6^th Korea National Health and Nutrition Examination Survey (2013 to 2015) was used in this study. There were 3,466 individuals aged between 40 and 80 years, with T2DM, who had a smoking and alcohol status listed, and blood analysis (including blood pressure), were included in this study. Lung function, measured by spirometer ventilatory dysfunction was categorized into 3 patterns: normal, restrictive ventilatory dysfunction, and obstructive ventilatory dysfunction (OVD).

Results

Based on multivariate logistic regression analysis, individuals with restrictive ventilatory dysfunction had an increased odds ratio (OR 1.615, 95% CI 1.137–2.294) for T2DM compared with individuals with normal ventilatory function, whereas OVD had no increase in the odds ratio (OR 1.169, 95 % CI 0.857–1.594). Model 1, which adjusted for age and gender, showed that the probability of having restrictive disorder was 1.559 times (95% CI 1.617–2.082) higher for prediabetes patients, and 2.320 times (95% CI 1.611–3.343) higher for T2DM patients, compared to normal individuals. For Model 4, which was fully adjusted for variables, the probability of having a restrictive disorder was 1.837 times higher for T2DM patients (95% CI 1.260–2.679).

Conclusion

Restrictive ventilatory dysfunction, but not OVD, was associated independently with T2DM.

Citations

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Idiopathic Pulmonary Fibrosis in Type 2 Diabetes Mellitus
Angelina Yuwono, Marcella Adisuhanto, Alius Cahyadi, Maxmillion Budiman, Alver Prasetya
Current Respiratory Medicine Reviews.2025; 21(2): 118. CrossRef
Effect of exercise training on cardiac autonomic function in type 2 diabetes mellitus: a systematic review and meta-analysis
Sohini Raje, G Arun Maiya, Padmakumar R, Mukund A. Prabhu, Krishnananda Nayak, Shivashankara KN, BA Shastry, Megha Nataraj
Systematic Reviews.2025;[Epub] CrossRef
Cardiorespiratory dynamics of type 2 diabetes mellitus: An extensive view of breathing and fitness challenges in a diabetes prevalent population
Uzair Abbas, Shahbaz Ali Shah, Nisha Babar, Pashmina Agha, Mohiba Ali Khowaja, Maryam Nasrumminallah, Hibba Erum Arif, Niaz Hussain, Syed Mustafa Hasan, Israr Ahmed Baloch, Hidetaka Hamasaki
PLOS ONE.2024; 19(7): e0303564. CrossRef
Evaluating the impact of type 2 diabetes mellitus on pulmonary vascular function and the development of pulmonary fibrosis
Nhlakanipho Mzimela, Nosipho Dimba, Aubrey Sosibo, Andile Khathi
Frontiers in Endocrinology.2024;[Epub] CrossRef
Causal relationship between type 2 diabetes and common respiratory system diseases: a two-sample Mendelian randomization analysis
Jie Chen, Xiaofeng Zhang, Gengyun Sun
Frontiers in Medicine.2024;[Epub] CrossRef
Hidden chronic metabolic acidosis of diabetes type 2 (CMAD): Clues, causes and consequences
Hayder A. Giha
Reviews in Endocrine and Metabolic Disorders.2023; 24(4): 735. CrossRef
Association of Pulmonary Function Decline over Time with Longitudinal Change of Glycated Hemoglobin in Participants without Diabetes Mellitus
Wen-Hsien Lee, Da-Wei Wu, Ying-Chih Chen, Yi-Hsueh Liu, Wei-Sheng Liao, Szu-Chia Chen, Chih-Hsing Hung, Chao-Hung Kuo, Ho-Ming Su
Journal of Personalized Medicine.2021; 11(10): 994. CrossRef

Enrolment Phase Results of the Tabari Cohort Study: Comparing Family History, Lipids and Anthropometric Profiles Among Diabetic Patients: Mahmood Moosazadeh, Mahdi Afshari, Kaveh Jafari, Motahareh Kheradmand, Zahra Kashi, Mohsen Aarabi, Adeleh Bahar, Mohammad Khademloo; Osong Public Health Res Perspect. 2019;10(5):289-294. Published online October 31, 2019; DOI: https://doi.org/10.24171/j.phrp.2019.10.5.05

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Abstract PDF

Objectives

Different factors are responsible for the silent epidemic of diabetes mellitus in developing and developed countries. This study aimed to determine the role of demographic factors, lipid profile, family history (the estimation of genetic association) and anthropometric factors on diabetes onset.

Methods

Data from the enrolment phase of the Tabari Cohort study was applied for this study and included 10,255 participants aged between 35–70 years. Anthropometric variables were measured by trained staff using standard tools. Blood specimens were collected for lipid profile and blood glucose measurements. Data analyses were performed using SPSS version 24, with univariate and multivariate logistic regression.

Results

The prevalence of diabetes mellitus was estimated to be 17.2% in the cohort population, 15.6% in men, and 18.3% in women. The adjusted odds ratios (95% confidence intervals) for age groups 40–49, 50–59 and over 60 were 2.58 (2.20–3.69), 5.80 (4.51–7.48) and 8.72 (6.67–11.39), respectively. In addition, the odds ratios (95% confidence intervals) for 2 (or more), and 1 affected family member were 4.12 (3.55–4.90) and 2.34 (2.07–2.65), respectively. Triglyceride concentrations more than 500, and abnormal high-density lipoprotein levels increased the odds of diabetes mellitus by 3.29- and 1.18-fold, respectively.

Conclusion

The current study showed that old age and a family history were strong predictors for diabetes mellitus.

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The prevalence and determinants of diabetes mellitus and thyroid disorder comorbidity in Tabari cohort population
Mahmood Moosazadeh, Saeedeh Khakhki, Adele Bahar, Akbar Hedayatizadeh-Omran, Motahareh Kheradmand, Reza Alizadeh-Navaei, Erfan Ghadirzadeh
Scientific Reports.2024;[Epub] CrossRef
Free-fatty acid receptor-4 gene polymorphism (rs61866610) and colorectal cancer risk
Ramin Shekarriz, Maryam Hasanian, Mohadeseh Ahmadi, Versa Omrani-Nava, Reza Alizadeh-Navaei
Nucleosides, Nucleotides & Nucleic Acids.2024; : 1. CrossRef
The relationship between spiritual intelligence and self-management in patients with diabetes type 1
Sima Rafiei, Saber Souri, Zahra Nejatifar, Mohammad Amerzadeh
BMC Endocrine Disorders.2023;[Epub] CrossRef
Prevalence and determinants of diabetes and prediabetes in southwestern Iran: the Khuzestan comprehensive health study (KCHS)
Sanam Hariri, Zahra Rahimi, Nahid Hashemi-Madani, Seyyed Ali Mard, Farnaz Hashemi, Zahra Mohammadi, Leila Danehchin, Farhad Abolnezhadian, Aliasghar Valipour, Yousef Paridar, Mohammad Mahdi Mir-Nasseri, Alireza Khajavi, Sahar Masoudi, Saba Alvand, Bahman
BMC Endocrine Disorders.2021;[Epub] CrossRef

Obesity, Hypertension, and Type-2 Diabetes Mellitus: The Interrelationships and the Determinants among Adults in Gaza City, Palestine: Mohammed S. Ellulu; Osong Public Health Res Perspect. 2018;9(6):289-298. Published online December 31, 2018; DOI: https://doi.org/10.24171/j.phrp.2018.9.6.02

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Abstract PDF

Objectives

To describe the distribution of social factors, lifestyle habits and anthropometric measurements according to hypertension and Type-2 diabetes.

Methods

A cross-sectional study was conducted in Gaza City, Palestine that included 379 patients (20–60 years) who had hypertension and/or diabetes. Three groups of patients were involved; 106 hypertensive (HT), 109 diabetic (T2DM) and 164 hypertensive diabetics (HT + T2DM).

Results

The HT + T2DM group were older and had a higher body mass index compared to HT and T2DM groups. There were 62.3% patients who were female, 49.2% were highly educated HT patients, and 49.3% patients had a low level of education and were HT + T2DM. There were 55.8% patients who lived in large families. Patients who were passive smokers or never smoked before were mostly HT + T2DM, while active smokers and past smokers had T2DM. There were 48.2% patients who were highly physically active who had HT, 40.9% whom were moderately active had T2DM, and 53.8% of patients who had a low level of activity were HT + T2DM. Multivariate linear regression showed that having a diseased mother, living in a large family, being a past or passive smoker, or never having smoked, having a low or moderate level of activity, and having HT or HT + T2DM, were significantly associated with an increased body mass index.

Conclusion

Parental health/disease conditions and environmental factors (social network and lifestyle habits) played the greatest role in the development of obesity and disease.

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Factors associated with physical inactivity among Palestinians with type 2 diabetes mellitus treated in resource-limited settings
Ramzi Shawahna, Mohammad Jaber, Arob Zmiro, Sewar Kashkoush
Scientific Reports.2024;[Epub] CrossRef
Time trends in Alzheimer’s disease mortality attributable to metabolic risks and smoking in China from 1990 to 2019: an age-period-cohort analysis
Simeng Sun, Ting Zhang, Hao Yu, Ting Xia, Yunan Yao, Mengting Sun, Hongmei Liang, Qiaoyu Huang, Weiwei Wang, Huafeng Yang, Xin Hong
Frontiers in Aging Neuroscience.2024;[Epub] CrossRef
Prevalence of hypertension and its associated factors among healthcare workers in the Gaza Strip, Palestine: a cross-sectional study
Joma Younis, Lina Wang, Kejing Zhang, Majed Jebril, Hong Jiang, Yahui Fan, Zhaofang Li, Mei Ma, Le Ma, Zhaozhao Hui, Mao Ma, Wei Zhang
BMJ Open.2024; 14(12): e076577. CrossRef
Analysis of the nutritional status in the Palestinian territory: a review study
Enas A. Assaf, Haleama Al Sabbah, Ayoub Al-Jawadleh
Frontiers in Nutrition.2023;[Epub] CrossRef
The hypertension cascade of care in the midst of conflict: the case of the Gaza Strip
Bassam A. Abu Hamad, Zeina Jamaluddine, Gloria Safadi, Marie-Elizabeth Ragi, Raeda El Sayed Ahmad, Eszter P. Vamos, Sanjay Basu, John S. Yudkin, Mohammed Jawad, Christopher Millett, Hala Ghattas
Journal of Human Hypertension.2022; 37(10): 957. CrossRef
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Roberta Fernanda da Silva, Riccardo Lacchini, Lucas Cezar Pinheiro, Letícia Perticarrara Ferezin, José Eduardo Tanus-Santos, Marcelo Rizzatti Luizon, Thiago José Dionísio, Carlos Ferreira Santos, Thaís Amanda Reia, André Mourão Jacomini, Ana Maria Guilmo
Clinical and Experimental Hypertension.2021; 43(7): 661. CrossRef
Breakfast characteristics, perception, and reasons of skipping among 8th and 9th-grade students at governmental schools, Jenin governance, West Bank
Manal Badrasawi, Ola Anabtawi, Yaqout Al-Zain
BMC Nutrition.2021;[Epub] CrossRef
Advanced Molecular Imaging (MRI/MRS/1H NMR) for Metabolic Information in Young Adults with Health Risk Obesity
Khin Thandar Htun, Jie Pan, Duanghathai Pasanta, Montree Tungjai, Chatchanok Udomtanakunchai, Thanaporn Petcharoen, Nattacha Chamta, Supak Kosicharoen, Kiattisak Chukua, Christopher Lai, Suchart Kothan
Life.2021; 11(10): 1035. CrossRef
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Cicily A. Gray, Omar T. Sims, Hyejung Oh
Journal of Racial and Ethnic Health Disparities.2020; 7(2): 365. CrossRef
Prevalence of Type 2 Diabetes and Its Association with Added Sugar Intake in Citizens and Refugees Aged 40 or Older in the Gaza Strip, Palestine
Majed Jebril, Xin Liu, Zumin Shi, Mohsen Mazidi, Akram Altaher, Youfa Wang
International Journal of Environmental Research an.2020; 17(22): 8594. CrossRef

Public Awareness of Early and Late Complications of Type 2 Diabetes - Application of Latent Profile Analysis in Determining Questionnaire Cut-Off Points: Nasrin Shirmohammadi, Ali Reza Soltanian, Shiva Borzouei; Osong Public Health Res Perspect. 2018;9(5):261-268. Published online October 31, 2018; DOI: https://doi.org/10.24171/j.phrp.2018.9.5.08

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Abstract PDF

Objectives

A questionnaire was designed to determine public understanding of early and late complications of Type 2 diabetes mellitus (T2DM).

Methods

A cross-sectional study was performed in participants who were selected using a multi-stage sampling method and a standard questionnaire of 67 questions was proposed. An expert panel selected 53 closed-ended questions for content validity to be included in the questionnaire. The reliability of the questionnaire was tested using Cronbach’s alpha coefficient giving a score of 0.84.

Results

Of the 825 participants, 443 (57.6%) were male, and 322 (41.87%) were 40 years or more. The proportion of low-, moderate- and high- awareness about T2DM and its complications was 29.26%, 62.68%, and 8.06%, respectively. Friends (56.31%) and internet and social networks (20.55%) were the 2 major sources of awareness, respectively. The medical staff (e.g., physicians) had the lowest share in the level of public awareness (3.64%) compared to other sources.

Conclusion

These results present data that shows the general population awareness of T2DM is low. Healthcare policymakers need to be effective at raising awarenes of diabetes and it should be through improved education.

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Polycytosine RNA-binding protein 1 regulates osteoblast function via a ferroptosis pathway in type 2 diabetic osteoporosis
Hong-Dong Ma, Lei Shi, Hai-Tian Li, Xin-Dong Wang, Mao-Wei Yang
World Journal of Diabetes.2024; 15(5): 977. CrossRef
Global burden of type 2 diabetes mellitus from 1990 to 2021, with projections of prevalence to 2044: a systematic analysis across SDI levels for the global burden of disease study 2021
Ke-Jie He, Haitao Wang, Jianguang Xu, Guoyu Gong, Xu Liu, Huiting Guan
Frontiers in Endocrinology.2024;[Epub] CrossRef
Healthcare Practitioners' Perspective of Prevailing Awareness on Diabetes Complications: A Questionnaire-Based Pan-India Study
Nikhil Tandon, Piya Ballani Thakkar, Jubbin Jacob, Pramila Kalra, Nanditha Arun, Alok Kanungo, Ashish Birla, Ashish Prasad, Mayuri Talathi
Cureus.2023;[Epub] CrossRef
What Is the Optimal Cut-Off Point of the 10-Item Center for Epidemiologic Studies Depression Scale for Screening Depression Among Chinese Individuals Aged 45 and Over? An Exploration Using Latent Profile Analysis
Hanlin Fu, Lulu Si, Ruixia Guo
Frontiers in Psychiatry.2022;[Epub] CrossRef
Classification of probable online social networking addiction: A latent profile analysis from a large-scale survey among Chinese adolescents
Ji-Bin Li, Anise M.S. Wu, Li-Fen Feng, Yang Deng, Jing-Hua Li, Yu-Xia Chen, Jin-Chen Mai, Phoenix K.H. Mo, Joseph T.F. Lau
Journal of Behavioral Addictions.2020; 9(3): 698. CrossRef

Factors that Correlate with Poor Glycemic Control in Type 2 Diabetes Mellitus Patients with Complications: Mohammad Haghighatpanah, Amir Sasan Mozaffari Nejad, Maryam Haghighatpanah, Girish Thunga, Surulivelrajan Mallayasamy; Osong Public Health Res Perspect. 2018;9(4):167-174. Published online August 31, 2018; DOI: https://doi.org/10.24171/j.phrp.2018.9.4.05

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Abstract PDF

Objectives

Inadequate glycemic control amongst patients with Type 2 diabetes mellitus (T2DM) indicates a major public health problem and a significant risk factor for the progression and complications caused by diabetes. Glycemic control is the main therapeutic objective for the prevention of organ damage and other complications arising from diabetes.

Methods

This was a retrospective observational study of T2DM patients with complications, who were aged 40 years and older. The study was conducted retrospectively on medical records (in-patient and out-patient) obtained from a South Indian teaching hospital, Manipal, India. The patients included in the study had fasting blood sugar, postprandial blood sugar and HbA1c measured at least twice during follow-ups the previous year. Patients’ HbA1c levels were categorized into good control ≤7% (≤53mmol/mol), and poor control >7% (>53mmol/mol), and patients’ characteristics were analyzed.

Results

A total of 657 patients were included in the study. The mean age was 59.67 (SD = 9.617) years, with 152 (23.1%) females and 505 (76.9%) males, and 514 (78.2%) patients had poor glycemic control. Most of the patients were on insulin mono-therapy [n = 271 (42.1%)], about a third of the patients were on combination therapy that included an oral hypoglycemic agent and insulin [n = 236 (36.6%)]. Patients with a history of more than 10 years of diabetes [n = 293 (44.6%)], had a family history of diabetes [n = 256 (39%)] and obesity [n = 95 (14.5%)], all had poor glycemic control.

Conclusion

This present study indicated a significant association of gender (female), age, high-density lipoprotein level, duration of diabetes and type of medication, with poor glycemic control in T2DM patients that had secondary medical complications.

Citations

Citations to this article as recorded by

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Effects of Physical Activity on Depression in Adults with Diabetes: Deok-Ju Kim; Osong Public Health Res Perspect. 2018;9(4):143-149. Published online August 31, 2018; DOI: https://doi.org/10.24171/j.phrp.2018.9.4.02

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Abstract PDF

Objectives

The purpose of this study was to identify the current state of physical activity in adults with diabetes and to investigate the effect of physical activity on depression.

Methods

The present study was conducted using data from the 2^nd year of the 6^th Korea National Health and Nutritional Examination Survey. From the total of 7,550 individuals, 418 adults diagnosed with diabetes were selected as participants, and their physical activity and depression levels were examined.

Results

The physical activity status of the participants showed that they did not usually engage in physical activities at work, and only a few participants were involved in moderate intensity physical leisure activity. Apart from walking for 10 minutes each day, which accounted for 1/3 of the participants, most of the participants did not engage in specific forms of exercise. An examination of the effects of physical activity on depression revealed that moderate intensity physical activity at work and leisure influenced depression. In terms of demographic characteristics, gender, occupation, income quintile, and subjective health status were all found to affect depression.

Conclusion

For elderly (60 years or older) patients with diabetes, which accounted for the majority of the diabetic population, a systematic leisure program and professional education are necessary to help them to manage stress and depression in daily life. Additionally, provision of community and family support should encourage regular, moderate intensity exercise and promote lifestyle changes to encourage increased physical activity.

Citations

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Brief Report

Imported Melioidosis in South Korea: A Case Series with a Literature Review: Seung Woo Kim, Geun-Yong Kwon, Bongyoung Kim, Donghyok Kwon, Jaeseung Shin, Geun-Ryang Bae; Osong Public Health Res Perspect. 2015;6(6):363-368. Published online December 31, 2015; DOI: https://doi.org/10.1016/j.phrp.2015.10.014

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Abstract PDF

Objectives
Melioidosis is a potentially fatal infectious disease caused by the environmental anaerobic Gram-negative bacillus Burkholderia pseudomallei. Melioidosis is endemic to areas of northern Australia and Southeast Asia. With increasing international travel and migration, imported cases of melioidosis are being reported regularly. Here, we summarize the 11 cases of melioidosis reported in South Korea from 2003 to 2014.
Methods
Tracing epidemiological investigations were performed on every patient reported to the National Surveillance System since 2011. A systematic literature search was performed to identify melioidosis cases that occurred prior to 2011.
Results
The overall fatality rate was 36.4%. All the patients had visited Southeast Asia where melioidosis is endemic. The stay in the endemic region ranged from 4 days to 20 years. Of the seven patients who developed initial symptoms after returning to South Korea, the time interval between returning to South Korea and symptom onset ranged from 1 day to 3 years. The remaining four patients developed symptoms during their stay in the endemic region and were diagnosed with melioidosis in South Korea. Seven (63.6%) patients possessed at least one risk factor, all of whom were diabetic. Pneumonia was the most frequent clinical manifestation, but the patients showed a wide spectrum of clinical features, including internal organ abscesses, a mycotic aneurysm of the aorta, and coinfection with tuberculosis.
Conclusion
An early diagnosis and initiation of the appropriate antibiotics can reduce the mortality of melioidosis. Consequently, increased awareness of the risk factors and clinical features of melioidosis is required.

Citations

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Co-Infections and Their Prognostic Impact on Melioidosis Mortality: A Systematic Review and Individual Patient Data Meta-Analysis
Pakpoom Wongyikul, Wiyada Kwanhian Klangbud, Moragot Chatatikun, Phichayut Phinyo
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An overview of the study designs and statistical methods used in the determination of predictors of melioidosis mortality in Malaysia: 2010-2021
Kamaruddin Mardhiah, Othman Nursyahiyatul-Anis
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Epidemiological Aspects of Imported Melioidosis in Korea and Japan, 2011 to 2020
Myeong-Jin Lee, Kyu Sung Kim, Won-Chang Lee, Young Hwan Kwon
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Original Article

Depression among Korean Adults with Type 2 Diabetes Mellitus: Ansan-Community-Based Epidemiological Study: Chan Young Park, So Young Kim, Jong Won Gil, Min Hee Park, Jong-Hyock Park, Yeonjung Kim; Osong Public Health Res Perspect. 2015;6(4):224-232. Published online August 31, 2015; DOI: https://doi.org/10.1016/j.phrp.2015.05.004

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21 Download
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Abstract PDF

Objectives
There are an increasing number of studies being carried out on depression in patients with diabetes. Individuals with diabetes have been reported as having a higher prevalence of depression compared to those without diabetes. However, only a few studies involving Korean patients have been conducted. The aims of this study were to examine the prevalence of depression and to find various risk factors according to the degree of depression among Korean patients with Type 2 diabetes mellitus (T2DM).
Methods
An Ansan-community-based epidemiological study was conducted from 2005 to 2012. The total number of participants in this study was 3,540, from which patients with diabetes (n = 753) have been selected. The presence of depression was evaluated using the Beck Depression Inventory total score.
Results
The prevalence of depression was 28.8%. The mean age of participants was 55.5 ± 8.2 years. We divided the participants into three groups (without-depression, moderate-depression, and severe-depression groups) to examine the depression prevalence among Korean T2DM patients. The unemployed participants had 2.40 [95% confidence interval (CI) 1.21–4.76], the low-income participants had 2.57 (95% CI 1.52–4.35), the participants using an oral diabetes medicine or insulin had 2.03 (95% CI 1.25–3.32), the participants who are currently smoking had 2.03 (95% CI 1.10–3.73), and those without regular exercise had 1.91 (95% CI 1.17–3.14) times higher odds of depression in the severe-depression group, compared with the without-depression group.
Conclusion
There was a significant association between depression prevalence and diabetes, and we found various risk factors according to the degree of depression in Korean patients with T2DM.

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