Osong Public Health and Research Perspectives

Original Article

Assessment of Intensive Vaccination and Antiviral Treatment in 2009 Influenza Pandemic in Korea: Chaeshin Chu, Sunmi Lee; Osong Public Health Res Perspect. 2015;6(1):47-51. Published online February 28, 2015; DOI: https://doi.org/10.1016/j.phrp.2014.11.007

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Objectives
We characterized and assessed public health measures, including intensive vaccination and antiviral treatment, implemented during the 2009 influenza pandemic in the Republic of Korea.
Methods
A mathematical model for the 2009 influenza pandemic is formulated. The transmission rate, the vaccination rate, the antiviral treatment rate, and the hospitalized rate are estimated using the least-squares method for the 2009 data of the incidence curves of the infected, vaccinated, treated, and hospitalized.
Results
The cumulative number of infected cases has reduced significantly following the implementation of the intensive vaccination and antiviral treatment. In particular, the intensive vaccination was the most critical factor that prevented severe outbreak.
Conclusion
We have found that the total infected proportion would increase by approximately six times under the half of vaccination rates.

Citations

Citations to this article as recorded by

Modeling influenza transmission dynamics with media coverage data of the 2009 H1N1 outbreak in Korea
Yunhwan Kim, Ana Vivas Barber, Sunmi Lee, Roberto Barrio
PLOS ONE.2020; 15(6): e0232580. CrossRef
Doing Mathematics with Aftermath of Pandemic Influenza 2009
Hae-Wol Cho, Chaeshin Chu
Osong Public Health and Research Perspectives.2015; 6(1): 1. CrossRef

Article

Sensitivity Analysis of the Parameters of Korea’s Pandemic Influenza Preparedness Plan: Chaeshin Chu, Junehawk Lee, Dong Hoon Choi, Seung-Ki Youn, Jong-Koo Lee; Osong Public Health Res Perspect. 2011;2(3):210-215. Published online December 31, 2011; DOI: https://doi.org/10.1016/j.phrp.2011.11.048

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25 Download
11 Crossref

Abstract PDF

Objectives
Our aim was to evaluate Korea’s Pandemic Influenza Preparedness Plan.
Methods
We conducted a sensitivity analysis on the expected number of outpatients and hospital bed occupancy, with 1,000,000 parameter combinations, in a situation of pandemic influenza, using the mathematical simulation program InfluSim.
Results
Given the available resources in Korea, antiviral treatment and social distancing must be combined to reduce the number of outpatients and hospitalizations sufficiently; any single intervention is not enough. The antiviral stockpile of 4–6% is sufficient for the expected eligible number of cases to be treated. However, the eligible number assumed (30% for severe cases and 26% for extremely severe cases) is very low compared to the corresponding number in European countries, where up to 90% of the population are assumed to be eligible for antiviral treatment.
Conclusions
A combination of antiviral treatment and social distancing can mitigate a pandemic, but will only bring it under control for the most optimistic parameter combinations.

Citations

Citations to this article as recorded by

A systematic literature review on public health and healthcare resources for pandemic preparedness planning
Berend H. H. Beishuizen, Mart L. Stein, Joeri S. Buis, Alma Tostmann, Caroline Green, Jim Duggan, Máire A. Connolly, Chantal P. Rovers, Aura Timen
BMC Public Health.2024;[Epub] CrossRef
Working memory capacity predicts individual differences in social-distancing compliance during the COVID-19 pandemic in the United States
Weizhen Xie, Stephen Campbell, Weiwei Zhang
Proceedings of the National Academy of Sciences.2020; 117(30): 17667. CrossRef
Assessment of Intensive Vaccination and Antiviral Treatment in 2009 Influenza Pandemic in Korea
Chaeshin Chu, Sunmi Lee
Osong Public Health and Research Perspectives.2015; 6(1): 47. CrossRef
Doing Mathematics with Aftermath of Pandemic Influenza 2009
Hae-Wol Cho, Chaeshin Chu
Osong Public Health and Research Perspectives.2015; 6(1): 1. CrossRef
Roll the Dice
Hae-Wol Cho, Chaeshin Chu
Osong Public Health and Research Perspectives.2014; 5(5): 243. CrossRef
Journal Publishing: Never Ending Saga
Hae-Wol Cho, Chaeshin Chu
Osong Public Health and Research Perspectives.2014; 5(1): 1. CrossRef
Summing Up Again
Hae-Wol Cho, Chaeshin Chu
Osong Public Health and Research Perspectives.2014; 5(4): 177. CrossRef
Years of Epidemics (2009–2011): Pandemic Influenza and Foot-and-Mouth Disease Epidemic in Korea
Hae-Wol Cho, Chaeshin Chu
Osong Public Health and Research Perspectives.2013; 4(3): 125. CrossRef
Public Health Crisis Preparedness and Response in Korea
Hye-Young Lee, Mi-Na Oh, Yong-Shik Park, Chaeshin Chu, Tae-Jong Son
Osong Public Health and Research Perspectives.2013; 4(5): 278. CrossRef
Was the Mass Vaccination Effective During the Influenza Pandemic 2009–2010 in Korea?
Hae-Wol Cho, Chaeshin Chu
Osong Public Health and Research Perspectives.2013; 4(4): 177. CrossRef
How to Manage a Public Health Crisis and Bioterrorism in Korea
Hae-Wol Cho, Chaeshin Chu
Osong Public Health and Research Perspectives.2013; 4(5): 223. CrossRef

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