Osong Public Health and Research Perspectives

Original Articles

Factors affecting depression and health-related quality of life in the elderly during the COVID-19 pandemic: Deok-Ju Kim; Osong Public Health Res Perspect. 2023;14(6):520-529. Published online November 16, 2023; DOI: https://doi.org/10.24171/j.phrp.2023.0166

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Graphical Abstract Abstract PDF: Objectives
This study investigated changes in the health behaviors of the elderly due to coronavirus disease 2019 (COVID-19), concerns due to COVID-19, depression, and healthrelated quality of life (HRQOL), and aimed to identify factors that affect depression and HRQOL in the elderly. Methods: This study was conducted using data from the 2021 Community Health Survey of the Korea Disease Control and Prevention Agency. From a total sample size of 229,242 individuals, 74,376 elderly people aged 65 or older were selected as subjects, and changes in health behaviors, concerns due to COVID-19, depression, and HRQOL were measured and analyzed. Results: The level of depression associated with sleep and fatigue was high. The lowest HRQOL was related to physical pain and discomfort, while the most common concerns were related to economic difficulties. Factors influencing depression included worries about infection and economic harm, while factors impacting HRQOL encompassed concerns about infection, economic harm, and criticism from others. Conclusion: If an infectious disease situation such as COVID-19 reoccurs in the future, it will be necessary to encourage participation in hybrid online and offline programs at senior welfare centers. This should also extend to community counseling institutions like mental health welfare centers. Additionally, establishing connections with stable senior job projects can help to mitigate the effects of social interaction restrictions, physical and psychological health issues, and economic difficulties experienced by the elderly.

Quality of life in patients treated for COVID-19–associated mucormycosis at a tertiary care hospital: Pragya Kumar, Rajath Rao UR, Nilanjan Roy, Deepika Agrawal, Shamshad Ahmad, Kranti Bhavana; Osong Public Health Res Perspect. 2023;14(2):119-128. Published online April 18, 2023; DOI: https://doi.org/10.24171/j.phrp.2022.0307

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Graphical Abstract Abstract PDF: Objectives
Coronavirus disease 2019 (COVID-19)–associated mucormycosis (CAM) has emerged as a formidable infection in patients with COVID-19. The aggressive management of CAM affects quality of life (QOL); thus, this study was designed to assess the QOL in patients with CAM at a tertiary healthcare institution.
Methods
This cross-sectional study of 57 patients with CAM was conducted over 6 months using a semi-structured standard questionnaire (the abbreviated World Health Organization Quality of Life questionnaire [WHO-BREF]) and a self-rated improvement (SRI) scale ranging from 0 to 9. Cut-off values of ≤52 and <7 were considered to indicate poor QOL and poor improvement, respectively. The correlations of QOL and SRI scores were evaluated using Spearman rho values.
Results
In total, 27 patients (47.4%; 95% confidence interval [CI], 34.9%–60.1%) and 26 patients (45.6%; 95% CI, 33.4%–58.4%) had poor QOL and poor SRI scores, respectively. The overall median (interquartile range) QOL score was 52 (41–63). Headache (adjusted B, −12.3), localized facial puffiness (adjusted B , −16.4), facial discoloration (adjusted B, −23.4), loosening of teeth (adjusted B, −18.7), and facial palsy (adjusted B, −38.5) wer e significantly associated with the QOL score in patients with CAM.
Conclusion
Approximately 1 in 2 patients with CAM had poor QOL and poor improvement. Various CAM symptoms were associated with QOL in these patients. Early recognition is the key to optimal treatment, improved outcomes, and improved QOL in patients with CAM.

Factors influencing quality of life in caregivers of adolescents with developmental disabilities: Joung Woo Joung; Osong Public Health Res Perspect. 2022;13(4):298-307. Published online August 31, 2022; DOI: https://doi.org/10.24171/j.phrp.2021.0158

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Abstract PDF: Objectives
Caring for adolescents with developmental disabilities (DD) is stressful and challenging, and mothers usually provide care for these children in Korea. This study aimed to identify factors influencing quality of life (QoL) in mothers of adolescents with DD.
Methods
A predictive design was used. Data were collected from a web-based survey administered to a convenience sample of 154 mothers of adolescents with DD from October to November 2020. Data were analyzed using the t-test, analysis of variance, Pearson correlation coefficients, and multiple regression.
Results
Perceived health, depression, and family strength were significantly correlated with QoL. Multiple regression showed that family strength, perceived health, depression, and monthly household income influenced the participants’ QoL, and these factors accounted for 69.2% of variance in QoL. Family strength was the factor most strongly affecting QoL (β=0.39).
Conclusion
The study results indicate that health professionals and policy-makers need to pay attention to the overall QoL and physical and psychological health of mothers of adolescents with DD. Since our findings raise the importance of family strength in the QoL of this population, programs to improve family strength need to be implemented and strengthened. Interventions to improve perceived health and decrease depression should be applied, and knowledge on adolescent characteristics and changes should be delivered to caregivers when providing education and consultations. The findings will be helpful for developing educational and counseling programs for this population.

Predictors of health-related quality of life in Koreans with cardiovascular disease: Jung-Hye Lim; Osong Public Health Res Perspect. 2022;13(1):62-70. Published online February 22, 2022; DOI: https://doi.org/10.24171/j.phrp.2021.0286

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Graphical Abstract Abstract PDF

Objectives
This study aimed to identify the predictors of health-related quality of life (HRQoL) in Korean adults with cardiovascular disease (CVD). Methods: This was a cross-sectional study with a stratified multistage probability sampling design. Data from the 2016 to 2019 Korea National Health and Nutrition Examination Survey (n=32,379) were used. Among the participants aged 19 years or older (n=25,995), 1,081 patients with CVD were extracted after excluding those with missing data and those who had cancer. The participants’ HRQoL was measured using the three-level EuroQoL Group’s five-dimension questionnaire (EQ-5D) scale. Data were analyzed using the t-test, one-way analysis of variance, and general linear regression for complex samples. Results: The most potent predictors of HRQoL in Korean adults with CVD were limited activity (β =−0.103, p <0.001), poor perceived health (β =−0.089, p <0.001), depression (β =−0.065, p<0.01), low household income (β=−0.033, p<0.05), unemployment (β=−0.023, p<0.05), and older age (β=−0.002, p<0.01), which explained 37.2% of the variance. Conclusion: Comprehensive interventions that address both physical and mental factors and social systems that provide financial help need to be implemented to improve the HRQoL of Korean adults with CVD.

Citations

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Factors associated with health-related quality of life in patients with coronary heart disease
Febio Gutama, Melisa Intan Barliana, Irma Melyani Puspitasari
Pharmacia.2022; 69(3): 771. CrossRef

Effects of activities of daily living-based dual-task training on upper extremity function, cognitive function, and quality of life in stroke patients: Hee-Su An, Deok-Ju Kim; Osong Public Health Res Perspect. 2021;12(5):304-313. Published online September 13, 2021; DOI: https://doi.org/10.24171/j.phrp.2021.0177

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Abstract PDF Supplementary Material

Objectives
The aim of this study was to investigate the effect of daily living dual-task training focused on improving attention and executive function of the upper extremities, cognitive function, and quality of life in stroke patients.
Methods
We included 30 stroke patients who were hospitalized between July 2020 and October 2020. They were divided into experimental and control groups through randomization. The experimental group performed 20 minutes of dual-task training and received 10 minutes of conventional occupational therapy, while the control group performed 20 minutes of single-task training and received 10 minutes of conventional occupational therapy. Both groups underwent their respective rehabilitation for 30 minutes per session, 5 times per week for 5 weeks.
Results
Both groups showed significant improvements in upper extremity function, cognitive function, and quality of life; the experimental group showed higher results for all items. A significant between-group difference was observed in the magnitude of the changes.
Conclusion
In stroke patients, dual-task training that combined attention and executive function with daily living activities was found to be meaningful, as it encouraged active participation and motivation. This study is expected to be used as a foundation for future interventions for stroke patients.

Citations

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Intervention and assessment of executive dysfunction in patients with stroke: A scoping review
Katsuya Sakai, Yuichiro Hosoi, Junpei Tanabe, Kathleen Bennett
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Occupation-based interventions to improve occupational performance and participation in the hospital setting: a systematic review
Gemma Wall, Stephen Isbel, Louise Gustafsson, Claire Pearce
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The effect of five activities daily living on improving cognitive function in ischemic stroke patients
Frana Andrianur, Dwi Prihatin Era, Arifin Hidayat, Ismansyah Ismansyah, Diah Setiani
Healthcare in Low-resource Settings.2023;[Epub] CrossRef
Effect of Upper Limb Motor Rehabilitation on Cognition in Parkinson’s Disease: An Observational Study
Valentina Varalta, Elisa Evangelista, Anna Righetti, Giovanni Morone, Stefano Tamburin, Alessandro Picelli, Cristina Fonte, Michele Tinazzi, Ilaria Antonella Di Vico, Andreas Waldner, Mirko Filippetti, Nicola Smania
Brain Sciences.2022; 12(12): 1684. CrossRef

Validity and reliability of the Health-Related Quality of Life Instrument with 8 Items (HINT-8) in Korean breast cancer patients: Juyoung Kim, Min-Woo Jo, Hyeon-Jeong Lee, Sei-Hyun Ahn, Byung Ho Son, Jong Won Lee, Sae Byul Lee; Osong Public Health Res Perspect. 2021;12(4):254-263. Published online August 5, 2021; DOI: https://doi.org/10.24171/j.phrp.2021.0005

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Abstract PDF Supplementary Material

Objectives
This study evaluated the validity and reliability of the Health-Related Quality of Life Instrument with 8 Items (HINT-8) in postoperative breast cancer patients in South Korea.
Methods
The study included 300 breast cancer patients visiting a tertiary hospital. We measured health-related quality of life (HRQoL) using the HINT-8, the 5-level EQ-5D version (EQ-5D-5L), and the Functional Assessment of Cancer Therapy-Breast (FACT-B). Discriminatory ability, known-group validity, and convergent validity were assessed. Reliability was evaluated with the Cohen kappa, weighted kappa, and intraclass correlation coefficient (ICC).
Results
The EQ-5D-5L indexes (p<0.001) and EQ visual analogue scale (VAS) scores (p<0.001) were significantly higher in subjects with no problems in each item of the HINT-8 than in those with problems. The FACT-B total scores were also higher in subjects without problems on the HINT-8. Older age, lower education level, and comorbidities were associated with a lower HINT-8 index. The HINT-8 index was correlated with the EQ-5D-5L index and the EQ VAS, with correlation coefficients of 0.671 (p<0.001) and 0.577 (p<0.001), respectively. The correlation coefficients between the HINT-8 and the FACT-B ranged from 0.390 to 0.714. The ICC was 0.690 (95% confidence interval, 0.580–0.780).
Conclusion
The HINT-8 showed appropriate validity for capturing HRQoL in postoperative breast cancer patients.

Citations

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Health-related quality of life of premenopausal young breast cancer survivors undergoing endocrine therapy
Kyungmi Lee, Hye Suk Jun
European Journal of Oncology Nursing.2024; 68: 102496. CrossRef
Smartphone application-based rehabilitation in patients with chronic respiratory and cardiovascular diseases
Chiwook Chung, Ah-Ram Kim, Dongbum Kim, Hee Kwon, Seong Ho Lee, Il-Young Jang, Min-Woo Jo, Do-Yoon Kang, Sei Won Lee
Scientific Reports.2024;[Epub] CrossRef
Willingness to pay for integrative healthcare services to treat sleep disturbances: Evidence from a nationwide survey
Min Kyung Hyun
European Journal of Integrative Medicine.2023; 58: 102223. CrossRef
Internal Structure of the Health-Related Quality of Life Instrument with 8-Items in a Nationally Representative Population
Eun-Hyun Lee
Journal of Korean Academy of Nursing.2023; 53(3): 359. CrossRef
Factors influencing health-related quality of life for young single-person households: the mediating effect of resilience
Soo Jin Lee, Sujin Lee, Xianglan Jin
Journal of Korean Biological Nursing Science.2023; 25(3): 160. CrossRef
Smartphone application-based rehabilitation in patients with chronic respiratory and cardiovascular diseases: a randomised controlled trial study protocol
Chiwook Chung, Ah-Ram Kim, Il-Young Jang, Min-Woo Jo, Seongho Lee, Dongbum Kim, Hee Kwon, Do-Yoon Kang, Sei Won Lee
BMJ Open.2023; 13(9): e072698. CrossRef
Health-related quality of life among cancer patients and survivors and its relationship with current employment status
Woorim Kim, Kyu-Tae Han, Seungju Kim
Supportive Care in Cancer.2022; 30(5): 4547. CrossRef
Associations between Food Groups and Health-Related Quality of Life in Korean Adults
Shamirah Nabbosa, Sunghee Lee
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Validity of the Health-Related Quality of Life Instrument with 8 Items (HINT-8) in the Korean Elderly: A Cross-Sectional Study
Seon-Ha Kim, Miok Kim
Journal of Korean Gerontological Nursing.2022; 24(3): 248. CrossRef

Impact of fatigue on quality of life among breast cancer patients receiving chemotherapy: Fares Mohammed Saeed Muthanna, Mahmathi Karuppannan, Bassam Abdul Rasool Hassan, Ali Haider Mohammed; Osong Public Health Res Perspect. 2021;12(2):115-125. Published online April 29, 2021; DOI: https://doi.org/10.24171/j.phrp.2021.12.2.09

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Abstract PDF

Objectives
Fatigue is the most frequently reported symptom experienced by cancer patients and has a profound effect on their quality of life (QOL). The study aimed to determine the impact of fatigue on QOL among breast cancer patients receiving chemotherapy and to identify the risk factors associated with severe fatigue incidence.
Methods
This was an observational prospective study carried out at multiple centers. In total, 172 breast cancer patients were included. The Functional Assessment of Chronic Illness Therapy-Fatigue Questionnaire was used to measure QOL, while the Brief Fatigue Inventory (BFI) was used to assess the severity of fatigue.
Results
The total average mean and standard deviation of QOL were 84.58±18.07 and 4.65±1.14 for BFI scores, respectively. A significant association between fatigue and QOL was found in linear and multiple regression analyses. The relationships between fatigue severity and cancer stage, chemotherapy dose delay, dose reduction, chemotherapy regimen, and ethnicity were determined using binary logistic regression analysis.
Conclusion
The findings of this study are believed to be useful for helping oncologists effectively evaluate, monitor, and treat fatigue related to QOL changes.

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Health-Related Quality of Life and its Associated Factors in COVID-19 Patients: Morteza Arab-Zozani, Fatemah Hashemi, Hossein Safari, Mahmood Yousefi, Hosein Ameri; Osong Public Health Res Perspect. 2020;11(5):296-302. Published online October 22, 2020; DOI: https://doi.org/10.24171/j.phrp.2020.11.5.05

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Abstract PDF

Objectives

Health-related quality of life (HRQoL) is one of the most important outcome measures for patients. The purpose of this study was to evaluate HRQoL and related factors in Coronavirus disease 2019 (COVID-19) patients.

Methods

A total of 420 COVID-19 patients who had been discharged from hospital were selected using a systematic sampling. The EuroQol 5-dimensional-5 levels (EQ-5D-5L) questionnaire along with medical records of the patients were used to gather the data. The t test and analysis of variance were employed to test the difference between mean EQ-5D-5L scores, and the BetaMix model was used to investigate factors associated with EQ-5D-5L scores.

Results

The mean score for the patients who completed the EQ-5D-5L questionnaire (n = 409) was 0.6125. The EQ-5D-5L scores were significantly higher in males, patients with younger age, those with a low level of education, the employed, patients who worked in uncrowded workplaces, patients without diabetes, and those who were not admitted to intensive care unit. The BetaMix model showed that gender, age, education, employment status, having diabetes, heart failure, and admission to the intensive care unit were significant independent predictors of the EQ-5D-5L index values.

Conclusion

The mean score for EQ-5D-5L in COVID-19 patients was low in this study. Some of the factors, especially aging and having diabetes, should be considered in the aftercare of patients to improve their HRQoL.

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Factors Influencing Self-Rated Oral Health in Elderly People Residing in the Community: Results from the Korea Community Health Survey, 2016: Jong-Hoon Moon, Sung-Jin Heo, Jin-Hwa Jung; Osong Public Health Res Perspect. 2020;11(4):245-250. Published online August 31, 2020; DOI: https://doi.org/10.24171/j.phrp.2020.11.4.14

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Abstract PDF

Objectives

The aim of this study was to examine the factors influencing perceived oral health in elderly individuals residing in the community.

Methods

This study used raw data from the Korea community health survey, 2016. Of the 64,223 participants that were elderly (aged ≥ 65 years), 61,280 (95.4%) were included for analysis. Self-rated oral health was the dependent variable and 6 independent variables including age, gender, type of area of residence (metropolitan or provincial), educational level, income, and living status with spouse were assessed. Oral function was studied based on mastication, pronunciation, and use of dentures, and oral health behavior included brushing teeth after breakfast, after lunch, after dinner, and before sleep). The EQ-5D questionnaire measured health-related quality of life (mobility, self-care, usual activities, pain/discomfort and anxiety/depression).

Results

Among the general characteristics, age, gender, educational level, income, and living status with spouse were the factors that affected self-rated oral health. Mastication, pronunciation, use of dentures, and brushing after lunch, dinner, and before sleep were the factors that influenced self-rated oral function. All domains of the EQ-5D (pain/discomfort, mobility, self-care, usual activities, and anxiety/depression) were factors that affected self-rated oral health.

Conclusion

The results of the current investigation suggest that the development of management and education strategies for oral health promotion in the elderly, should focus on improving oral function and oral health behavior, taking into account the socio-economic and demographic characteristics that have been shown to be associated with poor self-rated oral function.

Citations

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Older adults’ perceptions of oral health and its influence on general health: A deductive direct content analysis
Maria Snogren, Irene Eriksson, Maria Browall, Kristina Ek
Nordic Journal of Nursing Research.2023;[Epub] CrossRef
Oral health status and behavior in elderly Koreans with periodontal disease
Sae‐Rom Lee, Mi Ah Han, Jong Park, So Yeon Ryu, So Yeong Kim
Journal of Public Health Dentistry.2022; 82(4): 378. CrossRef
Oral health-related quality of life, probable depression and probable anxiety: evidence from a representative survey in Germany
André Hajek, Hans-Helmut König
BMC Oral Health.2022;[Epub] CrossRef
Factors Associated with Self‐reported Oral Health Among Community-Dwelling Older Adults in a Rural Province of Thailand
Yaowapa Chantaraboot, Nithimar Sermsuti-anuwat
Journal of Multidisciplinary Healthcare.2022; Volume 15: 2111. CrossRef
Self-rated oral health among elderly patients attending a university dental hospital in Thailand: a telephone-based cross-sectional survey study
Nithimar Sermsuti-anuwat, Narongrit Nampikul, Rawitsara Suwannimit, Weerachon Panthueng
PeerJ.2022; 10: e14191. CrossRef

Health-Related Quality of Life Based on Comorbidities Among Patients with End-Stage Renal Disease: Jieun Cha, Dallong Han; Osong Public Health Res Perspect. 2020;11(4):194-200. Published online August 31, 2020; DOI: https://doi.org/10.24171/j.phrp.2020.11.4.08

6,492 View
137 Download
11 Web of Science
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Abstract PDF

Objectives

The aim of this study was to investigate comorbidities in patients with end-stage renal disease, and to compare health-related quality of life (HRQOL) according to the type, and number of comorbidities.

Methods

A total of 250 adults undergoing hemodialysis were recruited at local clinics. HRQOL was measured using the 12-item Medical Outcomes Study Short Form questionnaire. Data were analyzed using descriptive statistics, analysis of variance, and t test.

Results

Around 70.8% of patients with end stage renal disease had 1 or more comorbidities, and the most common comorbidities were hypertension, diabetes, and cardiovascular disease. HRQOL was significantly different based on the number of comorbidities (F = 9.83, p < 0.001). The effect of comorbidities on the scores for mental health domains of the HRQOL questionnaire was not conclusive compared with the scores for the physical domain which were conclusive. Among the comorbidities, diabetes was associated with a lower quality of life.

Conclusion

The customized management of diabetic and hypertensive patients is necessary for the early detection and prevention of chronic kidney disease, and slowing the progression of renal disease and managing cardiovascular risk factors is essential.

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Abdulrahman R Al Tamimi, Bader A Aljaafri, Fahad Alhamad, Sultan Alhoshan, Awatif Rashidi, Basayel Dawsari, Ziad A Aljaafri
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Impact of Cognitive Aging on Health-Related Quality of Life in Menopausal Women: Kyoung Suk Lee, Mi Sook Jung, Mijung Kim, Kyeongin Cha, Eunyoung Chung; Osong Public Health Res Perspect. 2020;11(4):185-193. Published online August 31, 2020; DOI: https://doi.org/10.24171/j.phrp.2020.11.4.07

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Abstract PDF

Objectives

Menopause is a well-known risk factor for accelerating cognitive aging in women. This study aimed to assess differences in cognitive function and health-related quality of life (HRQOL) according to menopausal status to determine whether the menopause significantly affects the relationship between cognitive function and HRQOL.

Methods

This was a cross-sectional comparative study with a convenience sample of 178 Korean women including 89 naturally menopausal women (65 ± 10 years) and 89 non-menopausal women (45 ± 8 years) who met the eligibility criteria and completed neuropsychological tests and self-report questionnaires about their HRQOL, cognitive function, depression, and sleep quality. Multiple regression analyses were performed within and between groups according to menopausal status.

Results

Menopausal women had significantly worse scores on neuropsychological performance and HRQOL than non-menopausal women. A better neuropsychological performance (β = 0.34) was solely associated with a better HRQOL in menopausal women, whilst socioeconomic variables were associated with HRQOL in non-menopausal women.

Conclusion

Menopause is an important risk factor for HRQOL, and the association between cognition and HRQOL may differ according to menopausal status. When developing programs for target groups to improve daily functioning and HRQOL, healthcare professionals need to pay more attention to this relationship.

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Brain volumetric changes in menopausal women and its association with cognitive function: a structured review
Nur Zuliani Ramli, Mohamad Fairuz Yahaya, Nur Azlina Mohd Fahami, Hanani Abdul Manan, Meharvan Singh, Hanafi Ahmad Damanhuri
Frontiers in Aging Neuroscience.2023;[Epub] CrossRef

A Study on the Physical Activities, Mental Health, and Health-Related Quality of Life of Osteoarthritis Patients: Deok-Ju Kim; Osong Public Health Res Perspect. 2019;10(6):368-375. Published online December 31, 2019; DOI: https://doi.org/10.24171/j.phrp.2019.10.6.07

6,011 View
235 Download
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Abstract PDF

Objectives

The purpose of this study was to investigate the physical activities, mental health, and health-related quality of life (HRQOL) of osteoarthritis patients.

Methods

This study was conducted using data from the first year of the 7^th Korea National Health and Nutritional Examination Survey. There were 8,150 participants included in the survey, and 665 participants had been diagnosed with osteoarthritis. This study analyzed the measurements of physical activities, depression, and HRQOL in participants with osteoarthritis.

Results

The mean age of the participants was 67 ± 9.9 years and 83.1% were female. Participants rarely engaged in work-related physical activity, and engaged in leisure-related physical activities infrequently. Most of the participants (85.9%) did not do regular exercise, but 1/3 of the participants walked for over 10 minutes a day. “Pain/discomfort” had the least impact upon HRQOL, and among the depression subcategories, “difficult to sleep and tiredness” had the most impact. Multiple logistic regression analysis showed that an adverse HRQOL score was statistically significantly associated with “location changes/physical activities” (p < 0. 01), “depression” (p < 0.001) and “age” (p < 0.001).

Conclusion

Exercise programs should be in place which are manageable in everyday life for the elderly (> 65 years). Changes in daily routine so that patients become more active, should be supported by the family and community, together with assistance in managing psychological problems such as depression.

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Factors Affecting Activity Limitation in the Elderly: Data Processed from the Korea National Health and Nutrition Examination Survey, 2016: Jong-Hoon Moon; Osong Public Health Res Perspect. 2019;10(3):117-122. Published online June 30, 2019; DOI: https://doi.org/10.24171/j.phrp.2019.10.3.02

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Abstract PDF

Objectives

The aim of this study was to compare the sociodemographic characteristics, depression, and the health-related quality of life outcome, among the Korean elderly population, with and without activity limitation.

Methods

The data used was drawn from the raw data of the seventh Korea National Health and Nutrition Examination Survey (N = 8,150). There were 1,632 records for individuals aged 65 or older extracted from the seventh Korea National Health and Nutrition Examination Survey database, 199 of those had missing responses (n = 1,433). Differences within the sociodemographic characteristic, the Patient Health Questionnaire-9, and the EuroQol-5 Dimension were analyzed using logistic regression analysis according to the presence or absence of activity limitation.

Results

The prevalence of activity limitation among the elderly individuals surveyed was 19.9%. In the unadjusted regression analysis, the odds ratios of all independent variables (age, gender, education level, type of region, family income, the Patient Health Questionnaire-9, all 5 domains of the EuroQol-5 Dimension) between the elderly individuals with and without activity limitation, were significant. Although, in the adjusted logistic regression analysis, it was observed that the only factors that were significantly associated with activity limitation were the Patient Health Questionnaire-9, EuroQol-5 Dimension, type of region, and family income.

Conclusion

These findings demonstrated that activity limitation in elderly individuals is associated with the sociodemographic characteristics of family income and type of region of residence, as well as depression and the health-related quality of life outcome.

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R. López-Bueno, G.F. López-Sánchez, L. Smith, E. Sundstrup, L.L. Andersen, J.A. Casajús
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Journal of Clinical Medicine.2020; 9(3): 795. CrossRef

The Effects of Restricted Physical Activity on Health-Related Quality of Life in Adult Patients with Depression: Deok-Ju Kim; Osong Public Health Res Perspect. 2019;10(2):85-92. Published online April 30, 2019; DOI: https://doi.org/10.24171/j.phrp.2019.10.2.07

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Abstract PDF

Objectives

The objective was to identify restricted physical activity in patients with depression, and to determine the effects of that restricted activity, on their health-related quality of life (HRQOL).

Methods

Data was analysed from Year 1 of the 7th Korea National Health and Nutrition Examination Survey (KNHANES VII-1). From a total sample of 8,150 subjects, 277 adults aged ≥19 years who were diagnosed with depression were selected. The results were derived using restricted activity and HRQOL data measured from the subjects.

Results

Most of the participants were females ≥ 50 years old. HRQOL scores were high in the “self-care” dimension and low in the “pain/discomfort” and “anxiety/depression” dimensions. Their restricted activity due to illness in the past year, led to increases in participants being bedridden or absent from work. Many participants reported being bedridden for more than 3 months. A higher number of absences owing to illness in the past year, and longer durations of being bedridden, had a negative impact on HRQOL. Age, marital status, educational level, income level, and occupation were the sociodemographic variables that had an impact on HRQOL.

Conclusion

Patients with depression experiencing stress in their daily lives should take measures to avoid illness and pain that may lead to them becoming bedridden, and employ lifestyle habits with support from families and community health promotion centres, where mental health counselling can be accessed.

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Treatment with Sofosbuvir and Daclatasvir (with or without Ribavirin) Improves Patient Reported Outcomes in Hepatitis C: Lucas Pereira Jorge de Medeiros, Mario Barreto Correa Lima, Marcia Maria Amêndola Pires, Alessandra Mendonça Almeida Maciel, Renata Barboza Vianna Medeiros, Mariana Dermínio Donadel, Isabela Martins Becattini Pereira, Fábio Marchon Leão, Luiz Eduardo Amorim Correa Lima Pires, Helio Rzetelna, Carlos Eduardo Brandão-Mello; Osong Public Health Res Perspect. 2018;9(2):50-58. Published online April 30, 2018; DOI: https://doi.org/10.24171/j.phrp.2018.9.2.03

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38 Download
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Abstract PDF

Objectives

To evaluate the impact of 3 treatment regimens upon health-related quality of life and work productivity using patient-reported outcomes (PROs) in chronic hepatitis C infected patients: sofosbuvir (SOF) + daclatasvir (DCV); SOF + DCV + ribavirin (RBV); SOF + simeprevir (SMV).

Methods

4 questionnaires were used to evaluate PROs before, during and after treatment: Short Form-36 (SF-36), Chronic Liver Disease Questionnaire (CLDQ) - hepatitis C virus (HCV), Work Productivity and Activity Index, Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-F).

Results

Of the global sample of 55 patients included in this study; SOF + DCV (n = 10); SOF + DCV + RBV (n = 29); SOF + SMV (n = 16) all had a statistically significant improvement in SF-36, CLDQ and FACIT-F scores during and post-treatment. No statistically significant differences in the PRO questionnaire values were observed between the distinct treatment regimens. The SOF and SMV patient groups presented higher mean PRO variations during and post-treatment, compared to the other groups: SF-36 functional capacity (16.1); SF-36 mental health (21.4); CLDQ activity (1.8); CLDQ emotional function (1.2); FACIT-F physical well-being (8.0); Total FACIT-F (21.6).

Conclusion

Treatment with SOF + DCV, with or without RBV, results in an improved PRO similar to treatment with SOF + SMV in chronic hepatitis C patients.

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