Coronaviriniae Genera |
b-coronavirus, lineage B |
b-coronavirus, lineage C |
b-coronavirus, lineage B |
Virus type |
RNA virus |
RNA virus |
RNA virus |
Total length of DNA sequence |
29,751 |
30,111 |
29,903 |
Discovery (y) |
2003 |
2012 |
2019 |
Origin |
Guangdong province, China |
Arabian Peninsula |
Hubei province, China |
Total No. of cases worldwide (WHO report) |
> 8,000 |
2,494 |
2,230,439 (Till 17th April 2020) |
Total No. of affected countries (WHO report) |
26 |
27 |
210 |
Total number of death cases (WHO report) |
916 |
858 |
150,837 (As of 17th April 2020) |
Mortality |
>10% |
34.4% |
2.10% |
Transmission mode |
-Droplets (coughing and sneezing) -Close contact with an infected person |
-Droplets (coughing and sneezing) -Close contact with an infected person |
-Droplets (coughing and sneezing) -Close contact with an infected person or even asymptomatic ones |
Transmission medium |
Animal to human Human to human |
Animal to human Human to human |
Animal to human Human to human |
Transmission region |
Globally |
Regionally |
Globally |
Cellular receptor |
Angiotensin-Converting Enzyme 2 (ACE 2) |
Dipeptidyl peptidase 4 (DDP4) |
Angiotensin-Converting Enzyme 2 (ACE2) |
Reservoir |
Palm Civets and Bats |
Bats and Camels |
Bats |
Receptor binding domain (RBD) |
C-domain |
C-domain |
C-domain |
IFN-γ inhibitor |
Yes |
Yes |
Unknown |
Viral replication efficiency |
High |
Higher |
Higher |
Pathogenicity |
Higher |
High |
High |
Clinical symptoms (WHO report) |
Fever, malaise, myalgia, headache, diarrhea, and shivering (rigors) |
Fever, cough, and shortness of breath |
Fever, tiredness, and dry cough |
Prevention |
-Hand wash -Wear mask and gloves -Physical distancing |
-Hand wash -Wear mask and glove -Physical distancing |
-Hand wash -Wear mask and gloves -Physical distancing |
Treatment |
Glucocorticoid and interferon |
No vaccine or specific treatment |
No specific antiviral treatment |