Figure 1Monthly distribution of sample numbers tested and detections of Mycobacterium tuberculosis (culture results).
Table 1Locationwise data of total samples tested and positivity rates for Mycobacterium tuberculosis.
Location |
No. of samples tested |
No. of positive cultures |
Rate of positive culture (%) |
Seoul |
24,000 |
1,855 |
7.7 |
Busan |
16,595 |
790 |
4.8 |
Incheon |
9,626 |
483 |
5.0 |
Gyeonggi-do |
26,788 |
1,554 |
5.8 |
Gangwon-do |
13,815 |
295 |
2.1 |
Chungcheongbuk-do |
6,230 |
211 |
3.4 |
Chungcheongnam-do |
14,090 |
567 |
4.0 |
Jeollabuk-do |
6,982 |
291 |
4.2 |
Jeollanam-do |
18,319 |
460 |
2.5 |
Gyeongsangbuk-do |
12,899 |
679 |
5.3 |
Gyeongsangnam-do |
16,000 |
723 |
4.5 |
Jeju-do |
4,104 |
117 |
2.9 |
Osong (central center) |
792 |
191 |
24.1 |
Total |
170,240 |
8,216 |
4.8 |
Table 2Comparisons of smear microscopy, real-time PCR, and culture results.
|
Solid culture
|
Liquid culture
|
Smear microscopy |
Real-time PCR |
Smear microscopy |
Real-time PCR |
No. of samples |
167,538 |
3,692 |
10,144 |
1,583 |
True positive |
4,633 |
2,185 |
1,524 |
826 |
False positive |
684 |
298 |
105 |
51 |
True negative |
158,697 |
1,146 |
7,604 |
649 |
False negative |
3,524 |
63 |
911 |
57 |
Sensitivity (95% CI) |
56.8% (55.7–57.9) |
97.2% (96.4–97.84) |
62.6% (60.6–64.5) |
93.5% (91.7–95.1) |
Specificity (95% CI) |
99.6% (99.5–99.6) |
79.4% (77.2–81.4) |
98.6% (98.4–98.9) |
92.7% (90.5–94.5) |
p
|
<0.001 |
<0.001 |
<0.001 |
<0.001 |