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PHRP : Osong Public Health and Research Perspectives

OPEN ACCESS. pISSN: 2210-9099. eISSN: 2233-6052

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"intensive care units"

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"intensive care units"

Original Article
Epidemiological Study on Candida Species in Patients with Cancer in the Intensive Care Unit
Young-ju Choi, Byeongyeo Lee, Sun-A Park
Osong Public Health Res Perspect 2017;8(6):384-388.
Published online December 31, 2017
DOI: https://doi.org/10.24171/j.phrp.2017.8.6.05
<sec><title>Objectives</title><p>Although cancer survival rates have increased, serious infection complications can arise in cancer patients. <italic>Candida</italic> can occur in various tissues and has significant effects on the prognosis of patients with cancer. Thus, we conducted an epidemiological study on <italic>Candida</italic> infections in patients with cancer admitted to the intensive care unit.</p></sec><sec><title>Methods</title><p>A retrospective study was conducted in adult patients with cancer admitted to the intensive care unit between January 1, 2013, and December 31, 2015. <italic>Candida</italic> infection status and predictive factors for mortality were examined in 634 patients.</p></sec><sec><title>Results</title><p>The predictive factors for mortality included the use of steroids, use of a central venous catheter or mechanical ventilator, and identification of <italic>Candida</italic> in the blood. Patients who stayed in the surgical and intensive care unit for more than 7 days had a lower risk of death than that in those with shorter days.</p></sec><sec><title>Conclusion</title><p>The present study shows that invasive procedures, bloodstream infections, and the use of steroids increase the risk of mortality in <italic>Candida</italic>-infected patients with cancer. To improve the quality of life and reduce mortality, further studies are needed on the factors affecting the risk of mortality associated with <italic>Candida</italic> infection.</p></sec>

Citations

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  • Ionic Liquids with Anti-Candida and Anticancer Dual Activity as Potential N-Myristoyltransferase Inhibitors
    Larysa Metelytsia, Maria Trush, Ivan Semenyuta, Sergiy Rogalsky, Oleksandr Kobzar, Larisa Kalashnikova, Volodymyr Blagodatny, Diana Hodyna
    Current Bioactive Compounds.2020; 16(7): 1036.     CrossRef
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