<sec>
<title>Objectives</title>
<p>This study was conducted to evaluate whether a “smoking cessation intervention” education program based on blended learning, was effective in improving nursing students’ perceived competence and motivation to perform a smoking cessation intervention for smokers.</p></sec>
<sec>
<title>Methods</title>
<p>A quasi-experimental, pretest–posttest design was conducted. The smoking cessation intervention education program based on blended learning, was administered to the experimental group (<italic>n</italic> = 23) in 5 sessions, consisting of 2 courses of an e-learning program and 1 course of a face-to-face learning program per session. The control group (<italic>n</italic> = 21) received the opportunity to participate in an e-learning program as well as receiving material of a face-to-face learning program, after completion of the smoking cessation intervention education program.</p></sec>
<sec>
<title>Results</title>
<p>The experimental group showed significant differences in autonomous motivation (<italic>t</italic> = −6.982, <italic>p</italic> < 0.001), controlled motivation (<italic>t</italic> = −3.729, <italic>p</italic> = 0.001), and perceived competence compared to the control group (<italic>t</italic> = −3.801, <italic>p</italic> < 0.001).</p></sec>
<sec>
<title>Conclusion</title>
<p>This study showed that a smoking cessation intervention education program adopting blended learning, was significantly effective in enhancing nursing students’ autonomous motivation and perceived competence to conduct a smoking cessation intervention. Further studies are needed to confirm longitudinal effects of this program.</p></sec>
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