Department of Beauty Science, Kwangju Women’s University, Gwangju, Korea
Copyright © 2016 Korea Centers for Disease Control and Prevention. Published by Elsevier Korea LLC.
This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
Plant species | CC50∗ |
HRV2 |
HRV3 |
||
---|---|---|---|---|---|
IC50† | TI‡ | IC50† | TI‡ | ||
Z. piperitum | > 100 | 59.48 ± 5.01 | > 1.68 | 39.94 ± 0.27 | > 2.5 |
Z. schinifolium | 202.30 | 47.05 ± 18.02 | 4.3 | 47.48 ± 7.18 | 4.26 |
Z. coreanum | > 100 | ND§ | — | ND§ | — |
Z. planispinum | 345.35 | 66.55 ± 8.52 | 5.19 | 29.58 ± 7.58 | 11.68 |
Ribavirin | > 100 | 21.74 ± 1.53 | > 4.6 | 42.21 ± 9.21 | > 2.37 |
Plant species | CC50∗ |
CA16 |
CB3 |
CB4 |
EV71 |
||||
---|---|---|---|---|---|---|---|---|---|
IC50† | TI‡ | IC50† | TI‡ | IC50† | TI‡ | IC50† | TI‡ | ||
Z. piperitum | > 100 | 45.80 ± 2.45 | > 2.18 | 68.53 ± 4.72 | > 1.46 | 93.58 ± 2.74 | > 1.07 | 4.48 ± 0.90 | > 22.35 |
Z. schinifolium | > 100 | ND§ | — | ND§ | — | 70.02 ± 4.74 | > 1.43 | < 0.1 | > 1,000 |
Z. coreanum | > 100 | ND§ | — | 6.20 ± 0.70 | > 16.13 | ND§ | — | < 0.1 | > 1,000 |
Z. planispinum | 224.70 | ND§ | — | 39.87 ± 8.73 | 5.64 | 75.70 ± 6.34 | 2.97 | 56.05 ± 4.50 | 4.01 |
Ribavirin | 191.64 | ND§ | — | ND§ | — | ND§ | — | ND§ | — |
Results are presented as the mean IC50 values obtained from three independent experiments carried out in triplicate ± SD.
CA16 = coxsackie A16; CB3 = coxsackie B3; CB4 = coxsackie B4; EV71 = human enterovirus 71; HRV = human rhinovirus; IC50 = 50% inhibition concentration; ND = not determined; SD = standard deviation; TI = therapeutic index.