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Response to the comment of Perone by the corresponding author Kim
Yongmoon Kimorcid, Bryan Inho Kimorcid, Sangwoo Takorcid
Osong Public Health and Research Perspectives 2023;14(2):147-147.
Published online: March 24, 2023

Division of Risk Assessment, Bureau of Public Health Emergency Preparedness, Korea Disease Control and Prevention Agency, Cheongju, Republic of Korea

Yongmoon Kim, E-mail:
• Received: March 18, 2023   • Accepted: March 20, 2023

© 2023 Korea Disease Control and Prevention Agency.

This is an open access article under the CC BY-NC-ND license (

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I agree with Prof. Perone’s comment that his paper was referenced unproperly. His work should have been referenced in the next sentence, which is “or could not control for the effect of SARS-CoV-2 variants, especially during the emergence of the Delta and Omicron variants.” Our intention was to point out that we should consider the effect of COVID-19 variants when comparing different countries’ case fatality rates, complementing Perone’s preceding work, which showed the effect of environmental factors on the case fatality rate [1]. This was a mistake that happened during the revision process, and I offer my apologies to Prof. Perone.

Conflicts of Interest

The authors have no conflicts of interest to declare.

  • 1. Perone G. The determinants of COVID-19 case fatality rate (CFR) in the Italian regions and provinces: an analysis of environmental, demographic, and healthcare factors. Sci Total Environ 2021;755(Pt 1). 142523. ArticlePubMedPMC

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