<sec> <title>Objectives</title> <p>This study was performed to examine the effects of the Korean medicine healthcare program on stroke-related factors and self-care enhancement.</p></sec> <sec> <title>Methods</title> <p>This study was a quasi-experimental, pretest-posttest nonequivalent control group design study (<italic>N</italic> = 58 participants), with 28 in the treatment group (Korean medicine health care program) and 30 in the control group (no intervention). The program was conducted twice a week for 2 hours, for a total of 12 weeks.</p></sec> <sec> <title>Results</title> <p>There were statistically significant differences in systolic (<italic>p</italic> = 0.005) and diastolic blood pressure (<italic>p</italic> = 0.006), cholesterol (<italic>p</italic> < 0.001), blood glucose (<italic>p</italic> < 0.001), self-esteem (<italic>p</italic> = 0.001), self-efficacy (<italic>p</italic> < 0.001), health perception (<italic>p</italic> < 0.001), and the health behavior (<italic>p</italic> < 0.001) between the experimental group and the control group.</p></sec> <sec> <title>Conclusion</title> <p>Thus, the Korean medicine healthcare program was effective in managing stroke-related factors and enhancing self-care, and should be actively used to develop community health promotion strategies to prevent strokes and prepare long-term measures.</p></sec>