Osong Public Health and Research Perspectives

Original Articles

Genetic diversity and evolutionary patterns of SARS-CoV-2 among the Bhutanese population during the pandemic: Tshering Dorji, Kunzang Dorji, Tandin Wangchuk, Tshering Pelki, Sonam Gyeltshen; Osong Public Health Res Perspect. 2023;14(6):494-507. Published online December 14, 2023; DOI: https://doi.org/10.24171/j.phrp.2023.0209

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Graphical Abstract Abstract PDF: Objectives
The coronavirus disease 2019 (COVID-19) pandemic, caused by a dynamic virus, has had a profound global impact. Despite declining global COVID-19 cases and mortality rates, the emergence of new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants remains a major concern. This study provides a comprehensive analysis of the genomic sequences of SARS-CoV-2 within the Bhutanese population during the pandemic. The primary aim was to elucidate the molecular epidemiology and evolutionary patterns of SARS-CoV-2 in Bhutan, with a particular focus on genetic variations and lineage dynamics. Methods: Whole-genome sequences of SARS-CoV-2 collected from Bhutan between May 2020 and February 2023 (n=135) were retrieved from the Global Initiative on Sharing All Influenza Database. Results: The SARS-CoV-2 variants in Bhutan were predominantly classified within the Nextstrain clade 20A (31.1%), followed by clade 21L (20%) and clade 22D (15.6%). We identified 26 Pangolin lineages with variations in their spatial and temporal distribution. Bayesian time-scaled phylogenetic analysis estimated the time to the most recent common ancestor as February 15, 2020, with a substitution rate of 0.97×10–3 substitutions per site per year. Notably, the spike glycoprotein displayed the highest mutation frequency among major viral proteins, with 116 distinct mutations, including D614G. The Bhutanese isolates also featured mutations such as E484K, K417N, and S477N in the spike protein, which have implications for altered viral properties. Conclusion: This is the first study to describe the genetic diversity of SARS-CoV-2 circulating in Bhutan during the pandemic, and this data can inform public health policies and strategies for preventing future outbreaks in Bhutan.

Vaccine hesitancy in patients with COVID-19 who have back pain: Askeri Türken, Haşim Çapar; Osong Public Health Res Perspect. 2023;14(2):100-109. Published online March 24, 2023; DOI: https://doi.org/10.24171/j.phrp.2023.0003

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Objectives
Musculoskeletal pain is among the most common symptoms in patients diagnosed with coronavirus disease 2019 (COVID-19), and it has placed a significant burden on health worldwide during the pandemic. This study explored vaccine hesitancy and associated factors in patients with positive COVID-19 polymerase chain reaction test results who were hospitalized and had back pain.
Methods
A cross-sectional study was conducted among 170 hospitalized COVID-19 patients over 18 years of age. Data were analyzed using descriptive statistics with IBM SPSS ver. 25.0.
Results
COVID-19 patients who were married considered COVID-19 vaccinations riskier than unmarried COVID-19 patients. Patients who had not been vaccinated expressed higher levels of distrust towards COVID-19 vaccines than patients who had been vaccinated. Participants had relatively little hesitation toward the Sinovac vaccine. High vaccine confidence was found in all participants regardless of vaccination status. Those who had not received the COVID-19 vaccine reported higher risk perceptions than those who had received at least 1 dose of any COVID-19 vaccine.
Conclusion
Measurements of the hesitancy of vaccinated and non-vaccinated patients or members of society towards vaccines can be an important parameter for health authorities to find solutions.

Citations

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COVID-19 VE DAVRANIŞSAL İKTİSAT: KÜRESEL BİR PANDEMİ SIRASINDA İNSAN DAVRANIŞINI ANLAMAK
İlknur ARSLAN ARAS
Sağlık ve Sosyal Refah Araştırmaları Dergisi.2024; 6(1): 97. CrossRef

Review Article

SARS-CoV-2 in brief: from virus to prevention: Hassan Karami, Zeinab Karimi, Negin Karami; Osong Public Health Res Perspect. 2022;13(6):394-406. Published online November 28, 2022; DOI: https://doi.org/10.24171/j.phrp.2022.0155

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Abstract PDF

The recent outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), ahighly transmissible virus with a likely animal origin, has posed major and unprecedentedchallenges to millions of lives across the affected nations of the world. This outbreak firstoccurred in China, and despite massive regional and global attempts shortly thereafter, itspread to other countries and caused millions of deaths worldwide. This review presents keyinformation about the characteristics of SARS-CoV-2 and its associated disease (namely,coronavirus disease 2019) and briefly discusses the origin of the virus. Herein, we also brieflysummarize the strategies used against viral spread and transmission.

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Polysaccharides and Lectins: A Natural Complementary Approach against the SARS-CoV-2 Pandemic
Radu Lefter, Prairna Balyan, Ioana-Miruna Balmus, Abdellah Ech-Chahad, Ahmad Ali, Alin Ciobica, Antoneta Dacia Petroaie, Gabriela Halitchi, Bogdan Novac, Catalina Ionescu, Fatima Zahra Kamal
Microbiology Research.2024; 15(2): 525. CrossRef
Surveillance of endemic coronaviruses during the COVID‐19 pandemic in Iran, 2021–2022
Hassan Karami, Kaveh Sadeghi, Sevrin Zadheidar, Fatemeh Saadatmand, Negar Mirsalehi, Nima Hoveidi Ardestani, Shirin Kalantari, Mohammad Farahmand, Jila Yavarian, Talat Mokhtari‐Azad
Influenza and Other Respiratory Viruses.2023;[Epub] CrossRef

Short Communication

COVID-19 outbreak and risk factors for infection in a taekwondo gym in the Republic of Korea: Seung Hwan Shin, Eonjoo Park, Sookhyun Kim, Minji Jang, Subin Park, Dong-Hwi Kim, Tae Jong Son, Ji-Hyuk Park; Osong Public Health Res Perspect. 2022;13(2):162-170. Published online March 31, 2022; DOI: https://doi.org/10.24171/j.phrp.2021.0295

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Abstract PDF

Objectives
Relatively few studies have assessed risk factors for coronavirus disease 2019 (COVID-19) in public facilities used by children and adolescents. This study presents an analysis of a COVID-19 outbreak that occurred in a taekwondo gym in Korea, predominantly among children and adolescents, with the aim of providing insights on managing COVID-19 outbreaks in similar facilities. Methods: All 108 taekwondo gym students and staff received COVID-19 tests. A survey and closed-circuit television analyses were used to identify risk factors. A univariate analysis was conducted, followed by multivariate logistic regression analysis with backward elimination for variables with a significance level <0.10 in the univariate analysis. Results: COVID-19 was confirmed in 30 of 108 subjects at the taekwondo gym (attack rate, 27.8%). The outbreak started in an adult class student. This student transmitted the virus to the staff, who consequently transmitted the virus to adolescent students. In the univariate analysis, the relative risk for younger age (≤9 years) was 2.14 (95% confidence interval [CI], 1.01–4.54; p=0.054), and that for food consumption inside the gym was 2.12 (95% CI, 1.04–4.30; p=0.048). In the multivariate logistic regression analysis, the odds ratio for younger age was 2.96 (95% CI, 1.07–8.20; p=0.036), and that for food consumption inside the gym was 3.00 (95% CI, 1.10–8.17; p=0.032). Conclusion: Food consumption inside the facility and young age were significant risk factors for COVID-19 transmission in this taekwondo gym. Food consumption should be prohibited in sports facilities, and infection prevention education for young students is also required.

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The First Outbreak of Novel Coronavirus Disease 2019 (COVID-19) at an Outdoor Camping Site in South Korea, 2020
Na-Young Kim, Seonhee Ahn, GwangJin Kim, Donghyok Kwon, Young-Joon Park, Sang-Eun Lee
Journal of Epidemiology.2024; 34(4): 203. CrossRef
Risk evaluation of venue types and human behaviors of COVID-19 outbreaks in public indoor environments: A systematic review and meta-analysis
Weiwei Huang, Caroline X. Gao, Danting Luo, Yong Wang, Xiaohong Zheng, Cong Liu, Ying Wang, Yuguo Li, Hua Qian
Environmental Pollution.2024; 341: 122970. CrossRef
SARS-CoV-2 transmission modes: Why and how contamination occurs around shared meals and drinks?
Aure Saulnier, Jean-Michel Wendling, Benoit Hermant, Didier Lepelletier
Food Microbiology.2023; 114: 104297. CrossRef
Risk factors for COVID-19 outbreaks in livestock slaughtering and processing facilities in Republic of Korea
Seongju Choi, Tae Jong Son, Yeon-Kyung Lee
Osong Public Health and Research Perspectives.2023; 14(3): 207. CrossRef
Protective facemask-induced facial thermal stress and breathing burden during exercise in gyms
Qilong Zhong, Jiyun Song, Dachuan Shi, Chung-Hin Dung
Building and Environment.2023; 244: 110840. CrossRef

Review Articles

Worldwide prevalence of fungal coinfections among COVID-19 patients: a comprehensive systematic review and meta-analysis: Saber Soltani, Milad Zandi, Samireh Faramarzi, Ramin Shahbahrami, Mohebat Vali, Sara Akhavan Rezayat, Reza Pakzad, Pooneh Malekifar, Iraj Pakzad, Neda Jahandoost, Jalal Moludi; Osong Public Health Res Perspect. 2022;13(1):15-23. Published online February 8, 2022; DOI: https://doi.org/10.24171/j.phrp.2021.0293

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Abstract PDF Supplementary Material: Microbial coinfections can increase the morbidity and mortality rates of viral respiratory diseases. Therefore, this study aimed to determine the pooled prevalence of fungal coinfections in coronavirus disease 2019 (COVID-19) patients. Web of Science, Medline, Scopus, and Embase were searched without language restrictions to identify the related research on COVID-19 patients with fungal coinfections from December 1, 2019, to December 30, 2020. A random-effects model was used for analysis. The sample size included 2,246 patients from 8 studies. The pooled prevalence of fungal coinfections was 12.60%. The frequency of fungal subtype coinfections was 3.71% for Aspergillus, 2.39% for Candida, and 0.39% for other. The World Health Organization’s Regional Office for Europe and Regional Office for Southeast Asia had the highest (23.28%) and lowest (4.53%) estimated prevalence of fungal coinfection, respectively. Our findings showed a high prevalence of fungal coinfections in COVID-19 cases, which is a likely contributor to mortality in COVID-19 patients. Early identification of fungal pathogens in the laboratory for COVID-19 patients can lead to timely treatment and prevention of further damage by this hidden infection.

The role of lipids in the pathophysiology of coronavirus infections: Milad Zandi, Parastoo Hosseini, Saber Soltani, Azadeh Rasooli, Mona Moghadami, Sepideh Nasimzadeh, Farzane Behnezhad; Osong Public Health Res Perspect. 2021;12(5):278-285. Published online October 15, 2021; DOI: https://doi.org/10.24171/j.phrp.2021.0153

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Graphical Abstract Abstract PDF

Coronaviruses, which have been known to cause diseases in animals since the 1930s, utilize cellular components during their replication cycle. Lipids play important roles in viral infection, as coronaviruses target cellular lipids and lipid metabolism to modify their host cells to become an optimal environment for viral replication. Therefore, lipids can be considered as potential targets for the development of antiviral agents. This review provides an overview of the roles of cellular lipids in different stages of the life cycle of coronaviruses.

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PEDV inhibits HNRNPA3 expression by miR-218-5p to enhance cellular lipid accumulation and promote viral replication
Xiaojie Shi, Qi Zhang, Naling Yang, Quanqiong Wang, Yanxia Zhang, Xingang Xu, Xiang-Jin Meng, Ying Fang
mBio.2024;[Epub] CrossRef
Orsay Virus Infection of Caenorhabditis elegans Is Modulated by Zinc and Dependent on Lipids
Luis Alberto Casorla-Perez, Ranya Guennoun, Ciro Cubillas, Bo Peng, Kerry Kornfeld, David Wang, Rebecca Ellis Dutch
Journal of Virology.2022;[Epub] CrossRef

Scrutiny of COVID-19 response strategies among severely affected European nations: Shine Stephen, Alwin Issac, Rakesh Vadakkethil Radhakrishnan, Jaison Jacob, VR Vijay, Sam Jose, SM Azhar, Anoop S. Nair, Nadiya Krishnan, Rakesh Sharma, Manju Dhandapani; Osong Public Health Res Perspect. 2021;12(4):203-214. Published online July 29, 2021; DOI: https://doi.org/10.24171/j.phrp.2021.0068

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Graphical Abstract Abstract PDF

Although the health care systems in Europe are considered the global benchmark, European nations were severely affected by the coronavirus disease 2019 (COVID-19) pandemic. This manuscript aimed to examine the strategies implemented to combat the COVID-19 pandemic by France, the United Kingdom, Spain, Italy, Germany, and Russia and their outcomes in terms of the number of cases, testing, and deaths. This is the first review of its kind that extensively analyzes the preparedness, mitigation, and response strategies against the COVID-19 pandemic adopted by these nations. This paper further suggests a strategic preparedness model for future pandemics. From the analysis, we found that a decentralized approach, prompt decision-making and timely execution, coordination between local health authorities, and public participation in the implementation of strategies could substantially reduce the case fatality rate. Nations with a high percentage of gross domestic product invested in the health sector, as well as more nurses, physicians, hospital beds, intensive care unit beds, and ventilators, better managed the pandemic. Instead, nations that postponed their pandemic response by delaying tracking, tracing, testing, quarantine, and lockdown were badly affected. The lessons learned from the present pandemic could be used as a guide to prepare for further pandemics.

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Psychological impact and development of autistic traits in children during the COVID 19 Pandemic: A study through Guardian
Waseem Iqbal, Mudassir Hassan, Parveez Ahmed Mir, Syed Kaiser
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The Safety of Covishield (ChAdOx1 nCoV-19) Vaccine after Three Doses Vaccination under Mass Vaccination Program of Government of India
Narinder Singh, Jaswinder Singh, Vikram Bhandari, Rahat Kumar
AMEI's Current Trends in Diagnosis & Treatment.2024; 7(2): 38. CrossRef
Antibody titre in infants of covid-19 infected mothers
Shivani Sharma, Pushkar Lal Meena, Rameshwar Lal Suman, Jaya Ninama
IP International Journal of Medical Paediatrics an.2023; 9(2): 68. CrossRef
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Javaid Ahmad Mir, Asmat Parveen, Suheel Rashid Wani, Tayyibah Nisar, Sakeena Majeed, Wahida Kausar, Basit Ul Islam
IP International Journal of Medical Paediatrics an.2022; 8(1): 15. CrossRef
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Rakesh Sharma, KusumK Rohilla, Lisa Chadha, Priyanka Malhotra, S Sharmila, Prasuna Jelly
Journal of Family Medicine and Primary Care.2021; 10(9): 3257. CrossRef
Post COVID-19 changes in the perception of the parents towards dentistry for their child
Nahid Iftikhar, Shalini Dixit, Aditi Yadav
IP International Journal of Medical Paediatrics an.2021; 7(3): 155. CrossRef
A comparative study of attitudes towards COVID-19 vaccination in the rural and urban population of Uttarakhand, India
Rakesh Sharma, Prasuna Jelly, Vishwas AS, Lisa Chadha, Vartika Saxena, Latika Mohan
Journal of Global Health Economics and Policy.2021;[Epub] CrossRef

Original Article

Global variation of COVID-19 mortality rates in the initial phase: Saman Hasan Siddiqui, Azza Sarfraz, Arjumand Rizvi, Fariha Shaheen, Mohammad Tahir Yousafzai, Syed Asad Ali; Osong Public Health Res Perspect. 2021;12(2):64-72. Published online April 29, 2021; DOI: https://doi.org/10.24171/j.phrp.2021.12.2.03

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Abstract PDF Supplementary Material

Objectives
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused devastation in over 200 countries. Italy, Spain, and the United States (US) were most severely affected by the first wave of the pandemic. The reasons why some countries were more strongly affected than others remain unknown. We identified the most-affected and less-affected countries and states and explored environmental, host, and infrastructure risk factors that may explain differences in the SARS-CoV-2 mortality burden.
Methods
We identified the top 10 countries/US states with the highest deaths per population until May 2020. For each of these 10 case countries/states, we identified 6 control countries/states with a similar population size and at least 3 times fewer deaths per population. We extracted data for 30 risk factors from publicly available, trusted sources. We compared case and control countries/states using the non-parametric Wilcoxon rank-sum test, and conducted a secondary cluster analysis to explore the relationship between the number of cases per population and the number of deaths per population using a scalable EM (expectation–maximization) clustering algorithm.
Results
Statistically significant differences were found in 16 of 30 investigated risk factors, the most important of which were temperature, neonatal and under-5 mortality rates, the percentage of under-5 deaths due to acute respiratory infections (ARIs) and diarrhea, and tuberculosis incidence (p<0.05)
Conclusion
Countries with a higher burden of baseline pediatric mortality rates, higher pediatric mortality from preventable diseases like diarrhea and ARI, and higher tuberculosis incidence had lower rates of coronavirus disease 2019-associated mortality, supporting the hygiene hypothesis.

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PLOS Global Public Health.2024; 4(1): e0002854. CrossRef
The effect of the urban exposome on COVID-19 health outcomes: A systematic review and meta-analysis
Laura Houweling, Anke-Hilse Maitland-Van der Zee, Judith C.S. Holtjer, Somayeh Bazdar, Roel C.H. Vermeulen, George S. Downward, Lizan D. Bloemsma
Environmental Research.2024; 240: 117351. CrossRef
Demographic Characteristics and Status of Vaccinated Individuals with a History of COVID-19 Infection Pre- or Post-Vaccination: A Descriptive Study of a Nationally Representative Sample in Saudi Arabia
Yazed AlRuthia, Haya F. Al-Salloum, Omar A. Almohammed, Amani S. Alqahtani, Hana A. Al-Abdulkarim, Yousef M. Alsofayan, Sami S. Almudarra, Sara H. AlQahtani, Abdullah Almutlaq, Khaled Alabdulkareem, Bander Balkhi, Hamoud T. Almutairi, Abdullah S. Alanazi,
Vaccines.2022; 10(2): 323. CrossRef
Temporal variation, socioeconomic status, and out‐of‐hospital deaths as factors that influence mortality rates among hospitalized COVID‐19 patients receiving ACEIs/ARBs
Owais M. Aftab, Anurag Modak, Jai C. Patel
The Journal of Clinical Hypertension.2022; 24(4): 519. CrossRef
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Brief Reports

Operating a National Hotline in Korea During the COVID-19 Pandemic: Rok Song, Yuh Seog Choi, Jae Young Ko; Osong Public Health Res Perspect. 2020;11(6):380-382. Published online December 22, 2020; DOI: https://doi.org/10.24171/j.phrp.2020.11.6.06

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Abstract PDF

The importance of effective communication cannot be overestimated during a pandemic. The Korea Disease Control and Prevention Agency national 1339 hotline has been in operation since the Middle East respiratory syndrome coronavirus outbreak in 2016. The hotline is open 24 hours a day, 7 days a week, 365 days a year, and provides accurate, reliable information based upon the Korea Disease Control and Prevention Agency guidelines in response to queries. During the coronavirus disease 2019 (COVID-19) pandemic, the 1339 hotline received callers’ questions about symptoms and the implications of their actions regarding the epidemic. Through the 1339 hotline, callers received the up-to-date information that enabled them to protect themselves as well as others from COVID-19. This public service may have influenced on reduced risk of virus transmission in Korea.

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Muhammad Atif Waheed, Lolwa Al Mannai, Hanan Khudadad, Jamil Alenbawi, Mariama Aminata Mansaray, Samya Al Abdulla
JMIR Formative Research.2024; 8: e42753. CrossRef
Mental health concerns and network structures of psychological helpline help-seekers during the COVID-19 pandemic in China: Pandemic stage differences
Lizu Lai, Jingqiang Tong, Yu-Tao Xiang, Lin Zhang, Zhihong Ren
Journal of Affective Disorders.2023; 323: 444. CrossRef
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Nour Mheidly, Nadine Y. Fares, Mohamad Y. Fares, Jawad Fares
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Mohamed Arafa, Walid El Ansari, Fadi Qasem, Abdulla Al Ansari, Mohammed Al Ateeq Al Dosari, Khalid Mukhtar, Mohamed Ali Alhabash, Khalid Awad, Khalid Al Rumaihi
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Noah T. Fongwen, Almighty Nchafack, Hana Rohan, Jason J. Ong, Joseph D. Tucker, Nadine Beckmann, Gwenda Hughes, Rosanna W. Peeling, Felix Bongomin
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Epidemiology, clinical spectrum, viral kinetics and impact of COVID‐19 in the Asia‐Pacific region
Kin On Kwok, Ying Huang, Margaret Ting Fong Tsoi, Arthur Tang, Samuel Yeung Shan Wong, Wan In Wei, David Shu Cheong Hui
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A Public-Private Partnership Model to Build a Triage System in Response to a COVID-19 Outbreak in Hanam City, South Korea: Seong Su Ku, Young June Choe; Osong Public Health Res Perspect. 2020;11(5):339-342. Published online October 22, 2020; DOI: https://doi.org/10.24171/j.phrp.2020.11.5.11

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Abstract PDF

A substantial, immediate healthcare burden for screening of Coronavirus disease 2019 (COVID-19) is created when large-scale outbreaks occur. There have been a series of measures to strengthen the screening process through robust public-private partnerships between Hanam City Public Health Center (PHC), the local medical association, and central/provincial government. A partnership between PHC and the local physician’s group in Hanam City established the Respiratory Clinic. The PHC provided the infrastructure for the Respiratory Clinic including medical facilities, supplies (i.e. personal protective equipment), and administrative support. A total of 11 registered physicians from the local physicians group agreed to participate in clinical service provided at the Respiratory Clinic. Any citizens with COVID-19 suspected respiratory symptoms call the COVID-19 hotline and visit the Respiratory Clinic if required. Responding to COVID-19 outbreaks will be a continual process, and the screening system is essential support to public health interventions, and crucial in the response to a surge in COVID-19 cases.

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Journal of Korean Medical Science.2023;[Epub] CrossRef
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Original Article

COVID-19 in Nursing Facilities: Experience in Republic of Korea: Rok Song, Hee-Sook Kim, Seok-Ju Yoo, Kwan Lee, Ji-Hyuk Park, Joon Ho Jang, Gyoung-Sook Ahn, Jun-Nyun Kim; Osong Public Health Res Perspect. 2020;11(4):164-169. Published online August 31, 2020; DOI: https://doi.org/10.24171/j.phrp.2020.11.4.04

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Abstract PDF

Objectives

Coronavirus disease 2019 (COVID-19) outbreaks in nursing facilities can easily lead to a high rate of infection and fatality. A surge in newly infected cases in the first quarter of 2020 in Gyeongsan-si, in the Republic of Korea, was followed by several outbreaks in nursing facilities in the same area. The aim of this study is to report on the epidemiological investigation and the management to reduce the infection rate in nursing facilities for older adults.

Methods

The municipal government and the Korea Centers for Disease Control and Prevention performed an epidemiological investigation into 5 nursing facilities that reported a high number of COVID-19 infection cases from February to May 2020. COVID-19 infected cases in the facilities were investigated to identify the infection routes, and the fatality rate of the 5 facilities.

Results

The 5 facilities had a combined fatality rate of 12.2% (9 deceased among the 74 infected cases). The median age of the deceased was 87 years old (range: 82–91). The infection was first identified on February 27^th, 2020, peaked on March 6^th, and was last detected on March 24^th, 2020.

Conclusion

Difficulties specific to such facilities included the delay in the recognition of symptoms and limitation in distancing. Tailored strategies such as daily monitoring of symptoms and proactive COVID-19 screening of quarantined residents, contributed to a decline in the infections in the facilities.

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Review Article

COVID-19: Weighing the Endeavors of Nations, with Time to Event Analysis: Shine Stephen, Alwin Issac, Jaison Jacob, VR Vijay, Rakesh Vadakkethil Radhakrishnan, Nadiya Krishnan; Osong Public Health Res Perspect. 2020;11(4):149-157. Published online August 31, 2020; DOI: https://doi.org/10.24171/j.phrp.2020.11.4.02

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Abstract PDF

The cataclysmic COVID-19 pandemic erupted silently causing colossal impact worldwide, the repercussions of which indicated a lackadaisical vigilance in preparation for such a pandemic. This review assessed the measures taken by nations to contain this pandemic. A literature review was conducted using Medline, Google Scholar, Science Direct, Scopus, and WHO website. There were 8 nations (selected from the GHS index list) appraised for containment strategies. This was achieved by using mortality rate (per million) as the primary endpoint. The nations which were proactive, initiated scientific strategies earlier with rigor, appeared to have succeeded in containing the pandemic, although it is still too early to arbitrate a verdict. The so called “pandemic war” mandates international, interdisciplinary, and interdepartmental collaboration. Furthermore, building trust and confidence between the government and the public, having transparent communication, information sharing, use of advanced research-technology, and plentiful resources are required in the fight against COVID-19.

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Editorial

The Impact of Social Distancing on the Transmission of Influenza Virus, South Korea, 2020: Young June Choe, Jong-Koo Lee; Osong Public Health Res Perspect. 2020;11(3):91-92. Published online June 1, 2020; DOI: https://doi.org/10.24171/j.phrp.2020.11.3.07

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Original Article

Cross-Country Comparison of Case Fatality Rates of COVID-19/SARS-COV-2: Morteza Abdullatif Khafaie, Fakher Rahim; Osong Public Health Res Perspect. 2020;11(2):74-80. Published online April 30, 2020; DOI: https://doi.org/10.24171/j.phrp.2020.11.2.03

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Abstract PDF Supplementary Material

Objectives

Case fatality rates (CFR) and recovery rates are important readouts during epidemics and pandemics. In this article, an international analysis was performed on the ongoing coronavirus disease 2019 (COVID-19) pandemic.

Methods

Data were retrieved from accurate databases according to the user’s guide of data sources for patient registries, CFR and recovery rates were calculated for each country. A comparison of CFR between countries with total cases ≥ 1,000 was observed for 12^th and 23^rd March.

Results

Italy’s CFR was the highest of all countries studied for both time points (12^th March, 6.22% versus 23^rd March, 9.26%). The data showed that even though Italy was the only European country reported on 12^rd March, Spain and France had the highest CFR of 6.16 and 4.21%, respectively, on 23^rd March, which was strikingly higher than the overall CFR of 3.61%.

Conclusion

Obtaining detailed and accurate medical history from COVID-19 patients, and analyzing CFR alongside the recovery rate, may enable the identification of the highest risk areas so that efficient medical care may be provided. This may lead to the development of point-of-care tools to help clinicians in stratifying patients based on possible requirements in the level of care, to increase the probabilities of survival from COVID-19 disease.

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Short Communication

Contact Transmission of COVID-19 in South Korea: Novel Investigation Techniques for Tracing Contacts: Osong Public Health Res Perspect. 2020;11(1):60-63. Published online February 28, 2020; DOI: https://doi.org/10.24171/j.phrp.2020.11.1.09

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Abstract PDF

In the epidemiological investigation of an infectious disease, investigating, classifying, tracking, and managing contacts by identifying the patient’s route are important for preventing further transmission of the disease. However, omissions and errors in previous activities can occur when the investigation is performed through only a proxy interview with the patient. To overcome these limitations, methods that can objectively verify the patient’s claims (medical facility records, Global Positioning System, card transactions, and closed-circuit television) were used for the recent ongoing coronavirus disease 2019 contact investigations in South Korea.

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Why many countries failed at COVID contact-tracing — but some got it right
Dyani Lewis
Nature.2020; 588(7838): 384. CrossRef
The Serial Interval of COVID-19 in Korea: 1,567 Pairs of Symptomatic Cases from Contact Tracing
Kwan Hong, Sujin Yum, Jeehyun Kim, Byung Chul Chun
Journal of Korean Medical Science.2020;[Epub] CrossRef
A Public Platform for Virtual IoT-Based Monitoring and Tracking of COVID-19
Younchan Jung, Ronnel Agulto
Electronics.2020; 10(1): 12. CrossRef
The feasibility of organ transplantation during the COVID-19 outbreak: experiences from South Korea
Juhan Lee, Eun Jin Kim, Kyong Ihn, Jae Geun Lee, Dong Jin Joo, Myoung Soo Kim, Soon Il Kim, Yu Seun Kim, Kyu Ha Huh
Korean Journal of Transplantation.2020; 34(4): 257. CrossRef

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