FigureAntibiotic multi-resistance patterns of E. coli strains isolated from patients with diarrhea and healthy individuals. DR = drug resistance.
Table 1Specimens collected for this study
Age groups |
Control (n = 110)
|
Patients with diarrhea (n = 95)
|
Male |
Female |
Male |
Female |
1–10 |
0 |
0 |
7 |
15 |
11–20 |
2 |
2 |
3 |
5 |
21–30 |
9 |
18 |
5 |
7 |
31–40 |
3 |
18 |
5 |
6 |
41–50 |
6 |
33 |
9 |
3 |
51–60 |
0 |
7 |
5 |
4 |
61+ |
3 |
9 |
10 |
11 |
|
Total |
23 |
87 |
44 |
51 |
Table 2Antibiotic resistance patterns of E. coli strains
Antimicrobial agents |
Antibiotic resistances (%) of isolates
|
People without diarrhea |
Patients with diarrhea |
ß-lactams |
AM |
77.3 |
76.5 |
|
ß-lactam/ß-lactamase inhibitor combinations |
SAM |
6.5 |
22.6 |
TZP |
12.5 |
0.9 |
|
Cephems |
CF |
30 |
42.9 |
FEP |
0.9 |
8.9 |
CTT |
0 |
0 |
CTX |
3.2 |
13.6 |
FOX |
3.7 |
2.3 |
|
Carbapenems |
IPM |
0 |
0 |
|
Aminoglycosides |
AN |
9.6 |
2.1 |
GM |
39.4 |
29.2 |
NN |
31 |
17.9 |
NET |
4.6 |
3.3 |
|
Tetracyclines |
TE |
66.5 |
66 |
|
Monobactams |
ATM |
1.4 |
9.4 |
|
Folate pathway inhibitors |
SXT |
58.3 |
44.8 |
Table 3Comparison of sex-based antibiotic resistance patterns of the E. coli strains isolated from patients with diarrhea
Antimicrobial agents |
Male
|
Female
|
No. of resistance |
No. of non-resistance |
Rate of resistance (%) |
No. of resistance |
No. of non-resistance |
Rate of resistance (%) |
AM |
36 |
8 |
82 |
40 |
11 |
78 |
SAM |
11 |
33 |
25 |
16 |
35 |
31 |
TZP |
1 |
43 |
2 |
1 |
50 |
2 |
CF |
26 |
18 |
59 |
29 |
22 |
57 |
FEP |
5 |
39 |
11 |
2 |
49 |
4 |
CTT |
0 |
44 |
0 |
0 |
51 |
0 |
CTX∗
|
10 |
34 |
23 |
4 |
47 |
8 |
FOX∗
|
4 |
40 |
9 |
0 |
51 |
0 |
IPM |
0 |
44 |
0 |
0 |
51 |
0 |
AN∗
|
4 |
40 |
9 |
0 |
51 |
0 |
GM |
18 |
26 |
41 |
18 |
33 |
35 |
NN |
12 |
32 |
27 |
6 |
45 |
12 |
NET∗
|
4 |
40 |
9 |
0 |
51 |
0 |
TE |
32 |
12 |
73 |
33 |
18 |
65 |
ATM |
5 |
39 |
11 |
2 |
49 |
4 |
SXT |
24 |
20 |
55 |
25 |
26 |
49 |
Table 4Comparison of age-based antibiotic resistance patterns of the E. coli strains isolated from patients with diarrhea
Antimicrobial agents |
Younger than 40-years-old age
|
Older than 40-years-old age
|
No. of resistance |
No. of non-resistance |
Rate of resistance |
No. of resistance |
No. of non-resistance |
Rate of resistance |
AM |
45 |
8 |
85 |
23 |
11 |
68 |
SAM∗ |
19 |
34 |
36 |
5 |
29 |
15 |
TZP |
0 |
53 |
0 |
2 |
32 |
6 |
CF |
31 |
22 |
58 |
18 |
16 |
53 |
FEP∗ |
1 |
52 |
2 |
5 |
29 |
15 |
CTT |
0 |
53 |
0 |
0 |
34 |
0 |
CTX |
5 |
48 |
9 |
6 |
28 |
18 |
FOX |
2 |
51 |
4 |
2 |
32 |
6 |
IPM |
0 |
53 |
0 |
0 |
34 |
0 |
AN |
2 |
51 |
4 |
2 |
32 |
6 |
GM |
19 |
34 |
36 |
15 |
19 |
44 |
NN |
8 |
45 |
15 |
8 |
26 |
24 |
NET |
2 |
51 |
4 |
2 |
32 |
6 |
TE |
36 |
17 |
68 |
25 |
9 |
74 |
ATM∗ |
1 |
52 |
2 |
5 |
29 |
15 |
SXT∗ |
32 |
21 |
60 |
13 |
21 |
38 |