Local reaction (injection site) |
|
|
Pain |
|
|
None |
29 (34.5) |
21 (34.4) |
Mild pain that does not interfere with daily life |
51 (60.7) |
30 (49.2) |
Interference with activities of daily living |
4 (4.8) |
10 (16.4) |
ED visit or hospitalization |
0 (0) |
0 (0) |
Swelling |
|
|
None or with a diameter of 2.5 cm or less |
62 (73.8) |
32 (52.5) |
With a diameter of 2.5−5 cm |
17 (20.2) |
19 (31.1) |
With a diameter of 5.1−10 cm or difficulty moving arm |
5 (6.0) |
7 (11.5) |
With a diameter of 5.1−10 cm or degree of interference with activities of daily |
0 (0) |
3 (4.9) |
Erythema (redness) |
|
|
None or with a diameter of 2.5 cm or less |
65 (77.4) |
31 (50.8) |
With a diameter of 2.5−5 cm |
15 (17.9) |
17 (27.9) |
With a diameter of 5.1−10 cm |
4 (4.8) |
10 (16.4) |
With a diameter of 10 cm or more |
0 (0) |
3 -(4.9) |
Systematic reaction |
|
|
Pyrexia |
|
|
None |
79 (94.0) |
55 (90.2) |
Fever of 38.4 ℃ or less |
5 (6.0) |
5 (8.2) |
Fever of 38.5−38.9 ℃ |
0 (0) |
1 (1.6) |
Fever of 39.0−40.0 ℃ |
0 (0) |
0 (0) |
Fever of 40.0 ℃ or less |
0 (0) |
0 (0) |
Dyspnea |
|
|
None |
84 (100.0) |
61 (100.0) |
Shortness of breathing not interfering with daily life |
0 (0) |
0 (0) |
ED visit due to breathing difficulty |
0 (0) |
0 (0) |
Fatigue |
|
|
None |
62 (73.8) |
41 (67.2) |
Mild fatigue, but does not interfere with daily life |
16 (19.0) |
15 (24.6) |
Interference with activities of daily living |
6 (7.1) |
5 (8.2) |
ED visit or hospitalization |
0 (0) |
0 (0) |
Headache |
|
|
None |
72 (85.7) |
52 (85.2) |
Mild headaches that do not require medical attention |
6 (7.1) |
3 (4.9) |
Managing pain with medicine; does not interfere with daily life |
4 (4.8) |
6 (9.8) |
Pain is not manageable with medicine; interference with activities of daily life |
2 (2.4) |
0 (0) |
ED visit or hospitalization |
0 (0) |
0 (0) |
Myalgia |
|
|
None |
65 (77.4) |
47 (77.0) |
Mild: does not interfere with daily life |
15 (17.9) |
11 (18.0) |
Interference with activities of daily living |
4 (4.8) |
3 (4.9) |
ED visit or hospitalization |
0 (0) |
0 (0) |
Gastrointestinal disorders |
|
|
Nausea |
|
|
None |
84 (100.0) |
61 (100.0) |
Mild nausea: does not interfere with daily life |
0 (0) |
0 (0) |
Vomiting 1−2 times/d |
0 (0) |
0 (0) |
Vomiting more than 3 times/d |
0 (0) |
0 (0) |
ED visit or hospitalization |
0 (0) |
0 (0) |
Diarrhea |
|
|
None |
81 (96.4) |
60 (98.4) |
1−2 times/d |
2 (2.4) |
1 (1.6) |
More than 6 times/day or received medical treatment |
0 (0) |
0 (0) |
ED visit or hospitalization |
0 (0) |
0 (0) |
Skin disorders (other than the injection site) |
|
|
Urticarial or erythema |
|
|
None |
82 (97.6) |
60 (98.4) |
Mild: does not interfere with daily life |
2 (2.4) |
1 (1.6) |
Interference with activities of daily living |
0 (0) |
0 (0) |
ED visit or hospitalization |
0 (0) |
0 (0) |
Swelling |
|
|
None |
77 (91.7) |
59 (96.7) |
Mild: does not interfere with daily life |
7 (8.3) |
2 (3.3) |
Interference with activities of daily living |
0 (0) |
0 (0) |
ED visit or hospitalization |
0 (0) |
0 (0) |
Neurologic disorders |
|
|
Syncope or seizure |
|
|
None |
82 (97.6) |
60 (98.4) |
Sweating and dizziness |
2 (2.4) |
1 (1.6) |
Loss of consciousness |
0 (0) |
0 (0) |
Injury due to syncope |
0 (0) |
0 (0) |
Seizure |
0 (0) |
0 (0) |
Febrile seizure |
0 (0) |
0 (0) |
Unconscious for a day or more after seizure |
0 (0) |
0 (0) |
ED visit or hospitalization |
0 (0) |
0 (0) |